Abstract
Objective: The purpose of the present study was to assess a group of patients with fibromyalgia (FM) and control subjects using the
personality questionnaire proposed by Cloninger and to determine possible changes in the Italian version of the Temperament and
Character Inventory Revised patterns of patients with FM after therapy with serotoninergic antidepressants (selective serotonin reuptake
inhibitors [SSRIs]).
Methods: Sixty patients with FM filled out the Temperament and Character Inventory Revised and Beck Depression Inventory before and
after 6-month therapy with SSRIs (escitalopram 10 mg, fluoxetine 20 mg, or paroxetine 20 mg). A total of 80 age-, sex-, and education levelmatched
healthy subjects were selected as a control group.
Results: Both in the pretreatment and posttreatment period, patients were found to have higher harm avoidance and lower self-directedness
scores than healthy controls. In addition, harm avoidance and self-directedness were state and trait dependent.
Conclusions: Depressive symptoms in patients with FM can be significantly decreased by treatment with SSRIs. A careful clinical
assessment and study of personality profile is needed to identify patients with FM who may benefit from antidepressant pharmacologic
therapy and specific psychotherapeutic interventions.
Lingua originale | Inglese |
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pagine (da-a) | 240-244 |
Numero di pagine | 5 |
Rivista | Comprehensive Psychiatry |
Volume | 84 |
DOI | |
Stato di pubblicazione | Pubblicato - 2009 |
Keywords
- character
- fibromyalgia
- serotonin reuptake inhibitors
- temperament