Ventricular arrhythmias induced by long-term use of ephedrine in two competitive athletes.

Michela Casella; Antonio Dello Russo; Gennaro Izzo; Maurizio Pieroni; Daniele Andreini; Eleonora Russo; Daniele Colombo; Fabrizio Bologna; Leonardo Bolognese; Paolo Zeppilli; Claudio Tondo

doi:10.1007/s00380-013-0455-6

Ventricular arrhythmias induced by long-term use of ephedrine in two competitive athletes.

Michela Casella, Antonio Dello Russo, Gennaro Izzo, Maurizio Pieroni, Daniele Andreini, Eleonora Russo, Daniele Colombo, Fabrizio Bologna, Leonardo Bolognese, Paolo Zeppilli, Claudio Tondo

Università Cattolica del Sacro Cuore

Risultato della ricerca: Contributo in rivista › Articolo in rivista

11 Citazioni (Scopus)

Abstract

Ephedrine is a sympathomimetic substance used by sportsmen as a doping substance because of its stimulating and slimming effects. We report two cases of ventricular arrhythmias induced by abuse of ephedrine in two competitive athletes. Endomyocardial biopsies guided by electroanatomic mapping revealed contraction-band necrosis, a myocardial injury frequently observed in cases of catecholamine excess. Our cases suggest that long-term abuse of ephedrine may result in myocardial damage, and that these structural alterations may promote areas of slow conduction favoring re-entrant ventricular tachyarrhythmias and a long-lasting risk of ventricular arrhythmias.

Lingua originale	English
pagine (da-a)	280-283
Numero di pagine	4
Rivista	Heart and Vessels
DOI	https://doi.org/10.1007/s00380-013-0455-6
Stato di pubblicazione	Pubblicato - 2015

Keywords

Endomyocardial biopsy
Ventricular arrhythmia

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10.1007/s00380-013-0455-6

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title = "Ventricular arrhythmias induced by long-term use of ephedrine in two competitive athletes.",

abstract = "Ephedrine is a sympathomimetic substance used by sportsmen as a doping substance because of its stimulating and slimming effects. We report two cases of ventricular arrhythmias induced by abuse of ephedrine in two competitive athletes. Endomyocardial biopsies guided by electroanatomic mapping revealed contraction-band necrosis, a myocardial injury frequently observed in cases of catecholamine excess. Our cases suggest that long-term abuse of ephedrine may result in myocardial damage, and that these structural alterations may promote areas of slow conduction favoring re-entrant ventricular tachyarrhythmias and a long-lasting risk of ventricular arrhythmias.",

keywords = "Endomyocardial biopsy, Ventricular arrhythmia, Endomyocardial biopsy, Ventricular arrhythmia",

author = "Michela Casella and {Dello Russo}, Antonio and Gennaro Izzo and Maurizio Pieroni and Daniele Andreini and Eleonora Russo and Daniele Colombo and Fabrizio Bologna and Leonardo Bolognese and Paolo Zeppilli and Claudio Tondo",

year = "2015",

doi = "10.1007/s00380-013-0455-6",

language = "English",

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journal = "Heart and Vessels",

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TY - JOUR

T1 - Ventricular arrhythmias induced by long-term use of ephedrine in two competitive athletes.

AU - Casella, Michela

AU - Dello Russo, Antonio

AU - Izzo, Gennaro

AU - Pieroni, Maurizio

AU - Andreini, Daniele

AU - Russo, Eleonora

AU - Colombo, Daniele

AU - Bologna, Fabrizio

AU - Bolognese, Leonardo

AU - Zeppilli, Paolo

AU - Tondo, Claudio

PY - 2015

Y1 - 2015

N2 - Ephedrine is a sympathomimetic substance used by sportsmen as a doping substance because of its stimulating and slimming effects. We report two cases of ventricular arrhythmias induced by abuse of ephedrine in two competitive athletes. Endomyocardial biopsies guided by electroanatomic mapping revealed contraction-band necrosis, a myocardial injury frequently observed in cases of catecholamine excess. Our cases suggest that long-term abuse of ephedrine may result in myocardial damage, and that these structural alterations may promote areas of slow conduction favoring re-entrant ventricular tachyarrhythmias and a long-lasting risk of ventricular arrhythmias.

AB - Ephedrine is a sympathomimetic substance used by sportsmen as a doping substance because of its stimulating and slimming effects. We report two cases of ventricular arrhythmias induced by abuse of ephedrine in two competitive athletes. Endomyocardial biopsies guided by electroanatomic mapping revealed contraction-band necrosis, a myocardial injury frequently observed in cases of catecholamine excess. Our cases suggest that long-term abuse of ephedrine may result in myocardial damage, and that these structural alterations may promote areas of slow conduction favoring re-entrant ventricular tachyarrhythmias and a long-lasting risk of ventricular arrhythmias.

KW - Endomyocardial biopsy

KW - Ventricular arrhythmia

KW - Endomyocardial biopsy

KW - Ventricular arrhythmia

UR - http://hdl.handle.net/10807/55367

U2 - 10.1007/s00380-013-0455-6

DO - 10.1007/s00380-013-0455-6

M3 - Article

SN - 0910-8327

SP - 280

EP - 283

JO - Heart and Vessels

JF - Heart and Vessels

ER -

Ventricular arrhythmias induced by long-term use of ephedrine in two competitive athletes.

Abstract

Keywords

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