Variation in acute phlogistic reactions in the skin of rabbit fetuses

Roberto Bracaglia, Maurizio Rotoli, Rosario Petrosino, G Montemari

Risultato della ricerca: Contributo in rivistaArticolo in rivista

10 Citazioni (Scopus)

Abstract

There is little in the literature on cutaneous inflammatory reactions in mammal fetuses. The subject now has practical import since advances in medical science allow surgical intervention in premature infants. A study was performed on 45 rabbit fetuses. They were inoculated in the derma of the dorsum with 0.01 ml of a 1% solution of carrageenan, a strong inflammatory drug. Treatment was performed on the nineteenth, twenty-third, and twenty-seventh days of pregnancy. Two rabbits were treated twenty-four hours after birth, and 6 adult rabbits were treated. Histological examination and a count of inflammatory cells were performed on each fetus. The results showed that, during fetal life, the cellular inflammatory reaction is low in the earliest stages but increases gradually during gestation. It is only after birth that there is a great increase, and even then the level remains lower than in adults.
Lingua originaleEnglish
pagine (da-a)175-179
Numero di pagine5
RivistaAnnals of Plastic Surgery
Volume9
Stato di pubblicazionePubblicato - 1982

Keywords

  • Animals
  • Animals, Newborn
  • Carrageenan
  • Female
  • Fetus
  • Gestational Age
  • Pregnancy
  • Rabbits
  • Skin

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