Uterine fibroid embolization efficacy and safety: 15 years experience in an elevated turnout rate center

Carmine Di Stasi, Riccardo Manfredi, Cesare Colosimo, Alessandro Cina, Francesco Rosella, Andrea Paladini, Sonia Amoroso, Daniela Romualdi

Risultato della ricerca: Contributo in rivistaArticolo in rivista

4 Citazioni (Scopus)

Abstract

OBJECTIVE: To evaluate effectiveness and safety of UFE as alternative to surgery, in treatment of uterine fibromatosis. METHODS/MATERIALS: 255 patients (aged 26-55) with symptomatic UF, indication for surgery, followed in our center (2000-2014), single or multiple fibroids, pain and/or functional/compressive disorders, underwent embolization: injection of PVA particles (150-900 μm) from distal portion of uterine arteries (ascending section). Primary end-point: flow-stop distally to injection site, disappearance of lesion design, preservation of flow in main trunk of UA. Secondary end-point: control of pain and functional/compressive disorders during follow-up (2-7 years). RESULTS: Procedure was performed bilaterally in 250 patients (98%). Mean duration: 47 min (average fluoroscopy: 10:50 min). Post-embolization pelvic pain (according with VAS score) was on average 2.2 at discharge (24 h). Follow-up at 2 years: resolution of menstrual disorders in 78% of patients and improvement in 14%; pain disappeared in 66%; significant improvement of menstrual flow and HCT/HB levels, decrease in total uterine (57.7%)/dominant fibroid (76.1%) volume. Recurrence in 18 patients. CONCLUSIONS: UFE represents an excellent alternative to surgical treatment: it is safe, tolerable and effective both in short and long term, with evident advantages in economic and social terms.
Lingua originaleEnglish
pagine (da-a)N/A-N/A
RivistaLA RADIOLOGIA MEDICA
Stato di pubblicazionePubblicato - 2018

Keywords

  • UFE efficacy
  • UFE safety
  • UFE versus surgery
  • Uterine fibroid
  • Uterine fibroid embolization

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