TY - JOUR
T1 - Usefulness of F-18 FDG PET/CT in the follow-up of POEMS syndrome after autologous peripheral blood stem cell transplantation
AU - Stefanelli, Antonella
AU - Treglia, Giorgio
AU - Leccisotti, Lucia
AU - Laurenti, Luca
AU - Luigetti, Marco
AU - Sabatelli, Mario
AU - Giordano, Alessandro
PY - 2012
Y1 - 2012
N2 - We report a case of a patient with relapse of POEMS syndrome (peripheral neuropathy, organomegaly, endocrinopathy, monoclonal plasma proliferative disorder, skin changes) that occurred 6 years after an autologous peripheral blood stem cell transplantation. F-18 FDG PET/CT showed several hypermetabolic as well as nonhypermetabolic bone lesions. Based on these findings, the patient was referred for radiotherapy to the hypermetabolic bone lesions. After autologous peripheral blood stem cell transplantation, F-18 FDG PET/CT may play a pivotal role in detecting new bone lesions in patients with POEMS syndrome, which may be treated by a focalized radiotherapy and/or systemic therapy.
AB - We report a case of a patient with relapse of POEMS syndrome (peripheral neuropathy, organomegaly, endocrinopathy, monoclonal plasma proliferative disorder, skin changes) that occurred 6 years after an autologous peripheral blood stem cell transplantation. F-18 FDG PET/CT showed several hypermetabolic as well as nonhypermetabolic bone lesions. Based on these findings, the patient was referred for radiotherapy to the hypermetabolic bone lesions. After autologous peripheral blood stem cell transplantation, F-18 FDG PET/CT may play a pivotal role in detecting new bone lesions in patients with POEMS syndrome, which may be treated by a focalized radiotherapy and/or systemic therapy.
KW - Autologous
KW - Fluorodeoxyglucose F18
KW - Follow-Up Studies
KW - Humans
KW - Male
KW - Middle Aged
KW - POEMS Syndrome
KW - Peripheral Blood Stem Cell Transplantation
KW - Positron-Emission Tomography and Computed Tomography
KW - Transplantation
KW - Whole Body Imaging
KW - Autologous
KW - Fluorodeoxyglucose F18
KW - Follow-Up Studies
KW - Humans
KW - Male
KW - Middle Aged
KW - POEMS Syndrome
KW - Peripheral Blood Stem Cell Transplantation
KW - Positron-Emission Tomography and Computed Tomography
KW - Transplantation
KW - Whole Body Imaging
UR - https://publicatt.unicatt.it/handle/10807/3651
UR - https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=84862506076&origin=inward
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84862506076&origin=inward
U2 - 10.1097/RLU.0b013e31823ea154
DO - 10.1097/RLU.0b013e31823ea154
M3 - Article
SN - 0363-9762
VL - 37
SP - 181
EP - 183
JO - Clinical Nuclear Medicine
JF - Clinical Nuclear Medicine
IS - 2
ER -