Use of matrix-assisted laser desorption ionization-time of flight mass spectrometry for caspofungin susceptibility testing of Candida and Aspergillus species

Maurizio Sanguinetti, Brunella Posteraro, Elena De Carolis, Antonietta Vella, Patrizia Posteraro, David S. Perlin

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

81 Citazioni (Scopus)

Abstract

Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) was evaluated for testing susceptibility to caspofungin of wild-type and fks mutant isolates of Candida and Aspergillus. Complete essential agreement was observed with the CLSI reference method, with categorical agreement for 94.1% of the Candida isolates tested. Thus, MALDI-TOF MS is a reliable and accurate method to detect fungal isolates with reduced caspofungin susceptibility.
Lingua originaleEnglish
pagine (da-a)2479-2483
Numero di pagine5
RivistaJournal of Clinical Microbiology
Volume50
DOI
Stato di pubblicazionePubblicato - 2012

Keywords

  • Caspofungin

Fingerprint Entra nei temi di ricerca di 'Use of matrix-assisted laser desorption ionization-time of flight mass spectrometry for caspofungin susceptibility testing of Candida and Aspergillus species'. Insieme formano una fingerprint unica.

Cita questo