Urotensin II receptor determines prognosis of bladder cancer regulating cell motility/invasion

Alessandro Sgambato, Renato Franco, Silvia Zappavigna, Vincenzo Gigantino, Amalia Luce, Monica Cantile, Margherita Cerrone, Gaetano Facchini, Sisto Perdonà, Sandro Pignata, Giuseppe Di Lorenzo, Sergio Chieffi, Giovanni Vitale, Marco De Sio, Gerardo Botti, Ali Munaim Yousif, Ettore Novellino, Paolo Grieco, Michele Caraglia

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

26 Citazioni (Scopus)

Abstract

Non Muscle Invasive Bladder Transitional Cancer (NMIBC) and Muscle Invasive Bladder Transitional Cancer (MIBC)/invasive have different gene profile and clinical course. NMIBC prognosis is not completely predictable, since the relapse rate is higher than 20%, even in the form of MIBC. The aim of this study is to evaluate if UTR expression can discriminate between NMIBC and MIBC and predict the risk of relapses in NMIBCs.
Lingua originaleEnglish
pagine (da-a)N/A-N/A
Numero di pagine1
RivistaJOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
Volume33
DOI
Stato di pubblicazionePubblicato - 2014

Keywords

  • Adult
  • Aged
  • Carcinoma, Transitional Cell
  • Cell Line, Tumor
  • Cell Movement
  • Cell Proliferation
  • Disease-Free Survival
  • Female
  • Gene Expression
  • Humans
  • Kaplan-Meier Estimate
  • Male
  • Middle Aged
  • Neoplasm Invasiveness
  • Neoplasm Recurrence, Local
  • Peptide Fragments
  • Prognosis
  • Receptors, G-Protein-Coupled
  • Tissue Array Analysis
  • Urinary Bladder Neoplasms
  • Urotensins

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