Upper gut heat shock proteins HSP70 and GRP78 promote insulin resistance, hyperglycemia, and non-alcoholic steatohepatitis

Giulia Angelini; Lidia Castagneto-Gissey; Serenella Salinari; Alessandro Bertuzzi; Danila Anello; Meenakshi Pradhan; Marlen Zschätzsch; Paul Ritter; Carel W. Le Roux; Francesco Rubino; Nicola Basso; Giovanni Casella; Stefan R. Bornstein; Valentina Tremaroli; Geltrude Mingrone

doi:10.1038/s41467-022-35310-5

Upper gut heat shock proteins HSP70 and GRP78 promote insulin resistance, hyperglycemia, and non-alcoholic steatohepatitis

Giulia Angelini, Lidia Castagneto-Gissey, Serenella Salinari, Alessandro Bertuzzi, Danila Anello, Meenakshi Pradhan, Marlen Zschätzsch, Paul Ritter, Carel W. Le Roux, Francesco Rubino, Nicola Basso, Giovanni Casella, Stefan R. Bornstein, Valentina Tremaroli, Geltrude Mingrone^*

^*Autore corrispondente per questo lavoro

Risultato della ricerca: Contributo in rivista › Articolo in rivista

Lingua originale	English
pagine (da-a)	7715-7735
Numero di pagine	21
Rivista	Nature Communications
Volume	13
DOI	https://doi.org/10.1038/s41467-022-35310-5
Stato di pubblicazione	Pubblicato - 2022

Keywords

hyperglycemia
insulin resistance
non-alcoholic steatohepatitis
shock proteins

Accesso al documento

10.1038/s41467-022-35310-5

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Cita questo

Angelini, G., Castagneto-Gissey, L., Salinari, S., Bertuzzi, A., Anello, D., Pradhan, M., Zschätzsch, M., Ritter, P., Le Roux, C. W., Rubino, F., Basso, N., Casella, G., Bornstein, S. R., Tremaroli, V., & Mingrone, G. (2022). Upper gut heat shock proteins HSP70 and GRP78 promote insulin resistance, hyperglycemia, and non-alcoholic steatohepatitis. Nature Communications, 13, 7715-7735. https://doi.org/10.1038/s41467-022-35310-5

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keywords = "hyperglycemia, insulin resistance, non-alcoholic steatohepatitis, shock proteins, hyperglycemia, insulin resistance, non-alcoholic steatohepatitis, shock proteins",

author = "Giulia Angelini and Lidia Castagneto-Gissey and Serenella Salinari and Alessandro Bertuzzi and Danila Anello and Meenakshi Pradhan and Marlen Zsch{\"a}tzsch and Paul Ritter and {Le Roux}, {Carel W.} and Francesco Rubino and Nicola Basso and Giovanni Casella and Bornstein, {Stefan R.} and Valentina Tremaroli and Geltrude Mingrone",

year = "2022",

doi = "10.1038/s41467-022-35310-5",

language = "English",

volume = "13",

pages = "7715--7735",

journal = "Nature Communications",

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Angelini, G, Castagneto-Gissey, L, Salinari, S, Bertuzzi, A, Anello, D, Pradhan, M, Zschätzsch, M, Ritter, P, Le Roux, CW, Rubino, F, Basso, N, Casella, G, Bornstein, SR, Tremaroli, V & Mingrone, G 2022, 'Upper gut heat shock proteins HSP70 and GRP78 promote insulin resistance, hyperglycemia, and non-alcoholic steatohepatitis', Nature Communications, vol. 13, pagg. 7715-7735. https://doi.org/10.1038/s41467-022-35310-5

TY - JOUR

T1 - Upper gut heat shock proteins HSP70 and GRP78 promote insulin resistance, hyperglycemia, and non-alcoholic steatohepatitis

AU - Angelini, Giulia

AU - Castagneto-Gissey, Lidia

AU - Salinari, Serenella

AU - Bertuzzi, Alessandro

AU - Anello, Danila

AU - Pradhan, Meenakshi

AU - Zschätzsch, Marlen

AU - Ritter, Paul

AU - Le Roux, Carel W.

AU - Rubino, Francesco

AU - Basso, Nicola

AU - Casella, Giovanni

AU - Bornstein, Stefan R.

AU - Tremaroli, Valentina

AU - Mingrone, Geltrude

PY - 2022

Y1 - 2022

KW - hyperglycemia

KW - insulin resistance

KW - non-alcoholic steatohepatitis

KW - shock proteins

KW - hyperglycemia

KW - insulin resistance

KW - non-alcoholic steatohepatitis

KW - shock proteins

UR - http://hdl.handle.net/10807/228633

U2 - 10.1038/s41467-022-35310-5

DO - 10.1038/s41467-022-35310-5

M3 - Article

SN - 2041-1723

VL - 13

SP - 7715

EP - 7735

JO - Nature Communications

JF - Nature Communications

ER -