Upper GI endoscopy in elderly patients: predictive factors of relevant endoscopic findings

Cesare Hassan, Marcello Anti, Marco Bianco, L Buri, A Zullo, Giuseppe Bersani, L Cipolletta, Ed Giulio, Gd Matteo, L Familiari, L Ficano, P Loriga, S Morini, V Pietropaolo, A Zambelli, Eugenia Grossi, F Tessari, M Intraligi, M. Buscema

Risultato della ricerca: Contributo in rivistaArticolo in rivista

9 Citazioni (Scopus)

Abstract

Elderly patients are at increased risk for peptic ulcer and cancer. Predictive factors of relevant endoscopic findings at upper endoscopy in the elderly are unknown. This was a post hoc analysis of a nationwide, endoscopic study. A total of 3,147 elderly patients were selected. Demographic, clinical, and endoscopic data were systematically collected. Relevant findings and new diagnoses of peptic ulcer and malignancy were computed. Both univariate and multivariate analyses were performed. A total of 1,559 (49.5%), 213 (6.8%), 93 (3%) relevant findings, peptic ulcers, and malignancies were detected. Peptic ulcers and malignancies were more frequent in >85-year-old patients (OR 3.1, 95% CI = 2.0-4.7, p = 0.001). The presence of dysphagia (OR = 5.15), weight loss (OR = 4.77), persistent vomiting (OR = 3.68), anaemia (OR = 1.83), and male gender (OR = 1.9) were significantly associated with a malignancy, whilst overt bleeding (OR = 6.66), NSAIDs use (OR = 2.23), and epigastric pain (OR = 1.90) were associated with the presence of peptic ulcer. Peptic ulcer or malignancies were detected in 10% of elderly patients, supporting the use of endoscopy in this age group. Very elderly patients appear to be at higher risk of such lesions.
Lingua originaleEnglish
pagine (da-a)N/A-N/A
RivistaINTERNAL AND EMERGENCY MEDICINE
DOI
Stato di pubblicazionePubblicato - 2011
Pubblicato esternamenteYes

Keywords

  • upper gi

Fingerprint Entra nei temi di ricerca di 'Upper GI endoscopy in elderly patients: predictive factors of relevant endoscopic findings'. Insieme formano una fingerprint unica.

Cita questo