Abstract
Objectives: To assess the performance of the power Doppler index
(PDI) compared to subjective judgment of the ultrasonographer in
the preoperative diagnosis of ovarian malignancy.
Methods: Eighty-two successive complex adnexal masses were
examined prospectively with power Doppler before surgical
treatment. The investigation was multicentric and included in a
large contrast-enhanced ultrasound European study. A vascularity
index based on the number of colored pixels, was estimated on
selected frames (defined region of interest covering the entire tumor)
of the tumors using an in-house color quantifying program. The
sensitivity and specificity of PDI, the resistance index and subjective
visual scoringwere compared using receiver operating characteristic
(ROC) curves.
Results: Histology identified 34 malignant tumors including 11
borderline tumors and 48 benign tumors. PDI was considerably
higher in malignant than in benign lesions: 21.88 (95% CI,
19.19 24.57) vs. 8.11 (95% CI, 6.09 10.19) for the benign tumors
and 11.63 (95% CI, 1.20 22.06) for borderline tumors. The PDI
cut-off value for differential diagnosis was set at 0.107 (10.7%
of the tumor colored). However, the sensitivity and specificity of
the PDI were quite low: 75% (95% CI, 72.9 90.7) and 60%
(95% CI, 56.3 92.5) respectively. Using logistic regression, visual
Doppler scoring alone (OR 6.14 (95% CI, 2.30 16.38), P = 0.0003)
or associated with gray-scale examination (OR 10.5 (95% CI,
3.19 34.54), P = 0.0001) performed better than PDI (OR 2.61
(95% CI, 1.06 6.43), P = 0.04).
Conclusions: The power Doppler index obtained using our color
quantifying software has discriminating power for adnexal masses,
but visual Doppler scoring performed best.
Lingua originale | English |
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pagine (da-a) | 431-431 |
Numero di pagine | 1 |
Rivista | ULTRASOUND IN OBSTETRICS & GYNECOLOGY |
Volume | 2007 |
Stato di pubblicazione | Pubblicato - 2007 |
Evento | 17th World Congress on Ultrasound
in Obstetrics and Gynecology - Firenze Durata: 7 ott 2007 → 11 ott 2007 |
Keywords
- Doppler index
- Ultrasonographer