Trends in virological and clinical outcomes in individuals with HIV-1 infection and virological failure of drugs from three antiretroviral drug classes: a cohort study

Andrea De Luca, D Costagliola, R Lodwick, B Ledergerber, C Torti, A Van Sighem, D Podzamczer, A Mocroft, M Dorrucci, B Masquelier, K Jansen, S De Wit, N Obel, G Fätkenheuer, G Touloumi, C Mussini, A Castagna, C Stephan, F García, R ZangerleX Duval, S Perez Hoyos, L Meyer, J Ghosn, C Fabre Colin, J Kjaer, G Chene, J Garup, A. Phillips

Risultato della ricerca: Contributo in rivistaArticolo in rivista

35 Citazioni (Scopus)

Abstract

Limited treatment options have been available for people with HIV who have had virological failure of the three original classes of HIV antiretroviral drugs-so-called triple-class virological failure (TCVF). However, introduction of new drugs and drug classes might have improved outcomes. We aimed to assess trends in virological and clinical outcomes for individuals with TCVF in 2000-09.
Lingua originaleEnglish
pagine (da-a)119-127
Numero di pagine9
RivistaThe Lancet Infectious Diseases
Volume12
DOI
Stato di pubblicazionePubblicato - 2012

Keywords

  • Adolescent
  • Adult
  • Anti-HIV Agents
  • CD4 Lymphocyte Count
  • Cohort Studies
  • Female
  • HIV Infections
  • HIV-1
  • Humans
  • Male
  • Middle Aged
  • RNA, Viral
  • Regression Analysis
  • Retrospective Studies
  • Young Adult

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