Treatment of pharyngeal non-Hodgkin lymphoma in a patient with Wiskott-Aldrich syndrome

Stefano Mastrangelo, Antonio Ruggiero, Palma Maurizi, Paola Coccia, Maria Scalzone, Riccardo Riccardi, Angelo Rosolen

Risultato della ricerca: Contributo in rivistaArticolo in rivista

8 Citazioni (Scopus)

Abstract

Wiskott-Aldrich syndrome (WAS) is characterized by primary immunodeficiency, thrombocytopenia and eczema. Patients with WAS have an increased risk to develop tumors. Non-Hodgkin lymphoma (NHL) represents the most common malignancy occurring in WAS-affected patients, diffuse-large-B-cell lymphoma is the most frequently encountered variant. We describe a case of a patient with WAS and NHL in the pharynx, an atypical tumor site presentation. The patient was successfully treated with a reduced dose chemotherapy regimen plus anti-CD20 monoclonal antibody. He is in complete remission 3 years from the start of treatment. Pediatr Blood Cancer 2012;59:318-319. © 2011 Wiley Periodicals, Inc.
Lingua originaleEnglish
pagine (da-a)318-319
Numero di pagine2
RivistaPEDIATRIC BLOOD & CANCER
Volume59
DOI
Stato di pubblicazionePubblicato - 2012

Keywords

  • Wiscott-Aldrich syndrome
  • pharyngeal non Hodgkin Lymphoma

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