Transradial versus Transfemoral Access for Hepatic Chemoembolization: Intrapatient Prospective Single-Center Study

Roberto Iezzi, Maurizio Pompili, Alessandro Posa, Brigida Eleonora Annicchiarico, Matteo Garcovich, Biagio Merlino, Elena Rodolfino, Vincenzo Pio Di Noia, Michele Basso, Alessandra Cassano, Carlo Antonio Barone, Antonio Gasbarrini, Riccardo Manfredi, Cesare Colosimo

Risultato della ricerca: Contributo in rivistaArticolo in rivista

21 Citazioni (Scopus)


Purpose To compare transfemoral approach (TFA) and transradial approach (TRA) in patients undergoing hepatic chemoembolization in terms of safety, feasibility, and procedural variables, including fluoroscopy time, radiation dose (reference air kerma [RAK]), and patient preference. Materials and Methods A single-center prospective intrapatient comparative study was conducted with 42 consecutive patients with hepatic malignancies who received 2 consecutive treatment sessions of unilobar hepatic chemoembolization within a 4-week interval over a 6-month period with both TRA and TFA. All procedures were performed by 1 interventional radiologist who assessed the eligibility of patients for inclusion in the study. The primary endpoint was intraprocedural conversion rate. Secondary endpoints were access site complications, angiographic and procedural variables, and evaluation of patient discomfort and preferences. Results A 100% technical success rate and a crossover rate of 0% were recorded. There were no major vascular complications and similar rates of minor complications (4.8% for TRA, 7.1% for TFA; P =.095), which were self-limited and without any clinical sequelae. TRA treatments required a significantly longer preparation time for the procedure (P =.008) with no significant differences for other procedural variables. Greater discomfort at the access route and patient inability to perform basic activities after the procedure were recorded for TFA (P <.001). TRA was preferred by 35 patients (35/42) for potential future transarterial procedures. Conclusions TRA is safe and feasible for transarterial hepatic chemoembolization, with high technical success, low overall complications, and improved patient comfort.
Lingua originaleEnglish
pagine (da-a)1234-1239
Numero di pagine6
RivistaJournal of Vascular and Interventional Radiology
Stato di pubblicazionePubblicato - 2017


  • Aged
  • Cardiology and Cardiovascular Medicine
  • Chemoembolization, Therapeutic
  • Feasibility Studies
  • Female
  • Femoral Artery
  • Fluoroscopy
  • Humans
  • Liver Neoplasms
  • Male
  • Pain Measurement
  • Prospective Studies
  • Punctures
  • Radial Artery
  • Radiation Dosage
  • Radiography, Interventional
  • Radiology, Nuclear Medicine and Imaging
  • Treatment Outcome


Entra nei temi di ricerca di 'Transradial versus Transfemoral Access for Hepatic Chemoembolization: Intrapatient Prospective Single-Center Study'. Insieme formano una fingerprint unica.

Cita questo