Transfusion strategies in non-bleeding critically ill adults: a clinical practice guideline from the European Society of Intensive Care Medicine

Alexander P. Vlaar; Simon Oczkowski; Sanne De Bruin; Marije Wijnberge; Massimo Antonelli; Cecile Aubron; Philippe Aries; Jacques Duranteau; Nicole P. Juffermans; Jens Meier; Gavin J. Murphy; Riccardo Abbasciano; Marcella Muller; Akshay Shah; Anders Perner; Sofie Rygaard; Timothy S. Walsh; Gordon Guyatt; J. C. Dionne; Maurizio Cecconi

doi:10.1007/s00134-019-05884-8

Transfusion strategies in non-bleeding critically ill adults: a clinical practice guideline from the European Society of Intensive Care Medicine

Alexander P. Vlaar, Simon Oczkowski, Sanne De Bruin, Marije Wijnberge, Massimo Antonelli^*, Cecile Aubron, Philippe Aries, Jacques Duranteau, Nicole P. Juffermans, Jens Meier, Gavin J. Murphy, Riccardo Abbasciano, Marcella Muller, Akshay Shah, Anders Perner, Sofie Rygaard, Timothy S. Walsh, Gordon Guyatt, J. C. Dionne, Maurizio Cecconi

^*Autore corrispondente per questo lavoro

Risultato della ricerca: Contributo in rivista › Articolo in rivista

18 Citazioni (Scopus)

Abstract

Objective: To develop evidence-based clinical practice recommendations regarding transfusion practices in non-bleeding, critically ill adults. Design: A task force involving 13 international experts and three methodologists used the GRADE approach for guideline development. Methods: The task force identified four main topics: red blood cell transfusion thresholds, red blood cell transfusion avoidance strategies, platelet transfusion, and plasma transfusion. The panel developed structured guideline questions using population, intervention, comparison, and outcomes (PICO) format. Results: The task force generated 16 clinical practice recommendations (3 strong recommendations, 13 conditional recommendations), and identified five PICOs with insufficient evidence to make any recommendation. Conclusions: This clinical practice guideline provides evidence-based recommendations and identifies areas where further research is needed regarding transfusion practices and transfusion avoidance in non-bleeding, critically ill adults.

Lingua originale	English
pagine (da-a)	1-24
Numero di pagine	24
Rivista	Intensive Care Medicine
Volume	2020
DOI	https://doi.org/10.1007/s00134-019-05884-8
Stato di pubblicazione	Pubblicato - 2020

Keywords

Coagulopathy
Critically ill
EPO
Guideline
Intensive care
Plasma
Platelets
Point of care
Red blood cells
Transfusion

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10.1007/s00134-019-05884-8

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Vlaar, A. P., Oczkowski, S., De Bruin, S., Wijnberge, M., Antonelli, M., Aubron, C., Aries, P., Duranteau, J., Juffermans, N. P., Meier, J., Murphy, G. J., Abbasciano, R., Muller, M., Shah, A., Perner, A., Rygaard, S., Walsh, T. S., Guyatt, G., Dionne, J. C., & Cecconi, M. (2020). Transfusion strategies in non-bleeding critically ill adults: a clinical practice guideline from the European Society of Intensive Care Medicine. Intensive Care Medicine, 2020, 1-24. https://doi.org/10.1007/s00134-019-05884-8

@article{4230d7d5b98546eba53e36bbcba98c1a,

title = "Transfusion strategies in non-bleeding critically ill adults: a clinical practice guideline from the European Society of Intensive Care Medicine",

abstract = "Objective: To develop evidence-based clinical practice recommendations regarding transfusion practices in non-bleeding, critically ill adults. Design: A task force involving 13 international experts and three methodologists used the GRADE approach for guideline development. Methods: The task force identified four main topics: red blood cell transfusion thresholds, red blood cell transfusion avoidance strategies, platelet transfusion, and plasma transfusion. The panel developed structured guideline questions using population, intervention, comparison, and outcomes (PICO) format. Results: The task force generated 16 clinical practice recommendations (3 strong recommendations, 13 conditional recommendations), and identified five PICOs with insufficient evidence to make any recommendation. Conclusions: This clinical practice guideline provides evidence-based recommendations and identifies areas where further research is needed regarding transfusion practices and transfusion avoidance in non-bleeding, critically ill adults.",

keywords = "Coagulopathy, Critically ill, EPO, Guideline, Intensive care, Plasma, Platelets, Point of care, Red blood cells, Transfusion, Coagulopathy, Critically ill, EPO, Guideline, Intensive care, Plasma, Platelets, Point of care, Red blood cells, Transfusion",

author = "Vlaar, {Alexander P.} and Simon Oczkowski and {De Bruin}, Sanne and Marije Wijnberge and Massimo Antonelli and Cecile Aubron and Philippe Aries and Jacques Duranteau and Juffermans, {Nicole P.} and Jens Meier and Murphy, {Gavin J.} and Riccardo Abbasciano and Marcella Muller and Akshay Shah and Anders Perner and Sofie Rygaard and Walsh, {Timothy S.} and Gordon Guyatt and Dionne, {J. C.} and Maurizio Cecconi",

year = "2020",

doi = "10.1007/s00134-019-05884-8",

language = "English",

volume = "2020",

pages = "1--24",

journal = "Intensive Care Medicine",

issn = "0342-4642",

publisher = "Berlin; Heidelberg: Springer.",

}

Vlaar, AP, Oczkowski, S, De Bruin, S, Wijnberge, M, Antonelli, M, Aubron, C, Aries, P, Duranteau, J, Juffermans, NP, Meier, J, Murphy, GJ, Abbasciano, R, Muller, M, Shah, A, Perner, A, Rygaard, S, Walsh, TS, Guyatt, G, Dionne, JC & Cecconi, M 2020, 'Transfusion strategies in non-bleeding critically ill adults: a clinical practice guideline from the European Society of Intensive Care Medicine', Intensive Care Medicine, vol. 2020, pagg. 1-24. https://doi.org/10.1007/s00134-019-05884-8

TY - JOUR

T1 - Transfusion strategies in non-bleeding critically ill adults: a clinical practice guideline from the European Society of Intensive Care Medicine

AU - Vlaar, Alexander P.

AU - Oczkowski, Simon

AU - De Bruin, Sanne

AU - Wijnberge, Marije

AU - Antonelli, Massimo

AU - Aubron, Cecile

AU - Aries, Philippe

AU - Duranteau, Jacques

AU - Juffermans, Nicole P.

AU - Meier, Jens

AU - Murphy, Gavin J.

AU - Abbasciano, Riccardo

AU - Muller, Marcella

AU - Shah, Akshay

AU - Perner, Anders

AU - Rygaard, Sofie

AU - Walsh, Timothy S.

AU - Guyatt, Gordon

AU - Dionne, J. C.

AU - Cecconi, Maurizio

PY - 2020

Y1 - 2020

N2 - Objective: To develop evidence-based clinical practice recommendations regarding transfusion practices in non-bleeding, critically ill adults. Design: A task force involving 13 international experts and three methodologists used the GRADE approach for guideline development. Methods: The task force identified four main topics: red blood cell transfusion thresholds, red blood cell transfusion avoidance strategies, platelet transfusion, and plasma transfusion. The panel developed structured guideline questions using population, intervention, comparison, and outcomes (PICO) format. Results: The task force generated 16 clinical practice recommendations (3 strong recommendations, 13 conditional recommendations), and identified five PICOs with insufficient evidence to make any recommendation. Conclusions: This clinical practice guideline provides evidence-based recommendations and identifies areas where further research is needed regarding transfusion practices and transfusion avoidance in non-bleeding, critically ill adults.

AB - Objective: To develop evidence-based clinical practice recommendations regarding transfusion practices in non-bleeding, critically ill adults. Design: A task force involving 13 international experts and three methodologists used the GRADE approach for guideline development. Methods: The task force identified four main topics: red blood cell transfusion thresholds, red blood cell transfusion avoidance strategies, platelet transfusion, and plasma transfusion. The panel developed structured guideline questions using population, intervention, comparison, and outcomes (PICO) format. Results: The task force generated 16 clinical practice recommendations (3 strong recommendations, 13 conditional recommendations), and identified five PICOs with insufficient evidence to make any recommendation. Conclusions: This clinical practice guideline provides evidence-based recommendations and identifies areas where further research is needed regarding transfusion practices and transfusion avoidance in non-bleeding, critically ill adults.

KW - Coagulopathy

KW - Critically ill

KW - EPO

KW - Guideline

KW - Intensive care

KW - Plasma

KW - Platelets

KW - Point of care

KW - Red blood cells

KW - Transfusion

KW - Coagulopathy

KW - Critically ill

KW - EPO

KW - Guideline

KW - Intensive care

KW - Plasma

KW - Platelets

KW - Point of care

KW - Red blood cells

KW - Transfusion

UR - http://hdl.handle.net/10807/147686

U2 - 10.1007/s00134-019-05884-8

DO - 10.1007/s00134-019-05884-8

M3 - Article

SN - 0342-4642

VL - 2020

SP - 1

EP - 24

JO - Intensive Care Medicine

JF - Intensive Care Medicine

ER -

Transfusion strategies in non-bleeding critically ill adults: a clinical practice guideline from the European Society of Intensive Care Medicine

Abstract

Keywords

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