TY - JOUR
T1 - Transcutaneous bilirubin measurement: Comparison of Respironics BiliCheck and JM-103 in a normal newborn population
AU - Romagnoli, Costantino
AU - Zecca, Enrico
AU - Catenazzi, Piero
AU - Barone, Giovanni
AU - Zuppa, Antonio Alberto
PY - 2012
Y1 - 2012
N2 - OBJECTIVES: To compare the accuracy of BiliCheck™ (Respironics, Marietta, GA) and Konica-Minolta Air Shield JM-103 (Drager Medical Inc, Telford, PA) to evaluate total serum bilirubin (TSB).
METHODS: Prospective blinded study comparing two diagnostic devices in 630 neonates requiring TSB measurement.
RESULTS: Linear regression analysis showed a good correlation between BiliCheck™ and TSB (r=0.8212) as well as between JM-103 and TSB (r=0.8686). BiliCheck shows a tendency to underestimate TSB. The mean difference in TSB-TcB was -1.4 mg/dL for BC (-4.7/+1.8 mg/dL) and 0.3 mg/dL for JM-103 (-2.6/+3.2mg/dL). ROC analysis for TSB≥ 12 mg/dL showed area under the curve for BiliCheck™ significantly lower than those for JM-103 (p<0.0001). JM-103 resulted less time expensive than BiliCheck.
CONCLUSIONS: In spite of similar diagnostic accuracy JM-103 could be preferred for some practical advantages, but its suitability in performing universal screening for severe hyperbilirubinemia deserves further investigations.
AB - OBJECTIVES: To compare the accuracy of BiliCheck™ (Respironics, Marietta, GA) and Konica-Minolta Air Shield JM-103 (Drager Medical Inc, Telford, PA) to evaluate total serum bilirubin (TSB).
METHODS: Prospective blinded study comparing two diagnostic devices in 630 neonates requiring TSB measurement.
RESULTS: Linear regression analysis showed a good correlation between BiliCheck™ and TSB (r=0.8212) as well as between JM-103 and TSB (r=0.8686). BiliCheck shows a tendency to underestimate TSB. The mean difference in TSB-TcB was -1.4 mg/dL for BC (-4.7/+1.8 mg/dL) and 0.3 mg/dL for JM-103 (-2.6/+3.2mg/dL). ROC analysis for TSB≥ 12 mg/dL showed area under the curve for BiliCheck™ significantly lower than those for JM-103 (p<0.0001). JM-103 resulted less time expensive than BiliCheck.
CONCLUSIONS: In spite of similar diagnostic accuracy JM-103 could be preferred for some practical advantages, but its suitability in performing universal screening for severe hyperbilirubinemia deserves further investigations.
KW - transcutaneo
KW - transcutaneo
UR - http://hdl.handle.net/10807/21374
U2 - 10.1016/j.clinbiochem.2012.03.014
DO - 10.1016/j.clinbiochem.2012.03.014
M3 - Article
SN - 0009-9120
VL - 45
SP - 659
EP - 662
JO - Clinical Biochemistry
JF - Clinical Biochemistry
ER -