Transanal total mesorectal excision (TaTME): single-centre early experience in a selected population

Michele De Rosa, Fabio Rondelli, Marcello Boni, Fabio Ermili, Walter Bugiantella, Lorenzo Mariani, Graziano Ceccarelli, Antonio Giuliani

Risultato della ricerca: Contributo in rivistaArticolo in rivista


Total mesorectal excision (TME) represents the key principle in the surgical treatment of rectal cancer. Transanal mesorectal excision was introduced as a complement to conventional surgery to overcome its technical difficulties. The aim of this study was to evaluate the early surgical results following the introduction of this novel technique at our Unit. Between January and May 2016, 12 patients diagnosed with mid-low rectal adenocarcinoma were enrolled into this study and evaluated with regards demography, histopathology, peri-operative data and postoperative complications. The tumor was located in the middle rectum in 6 patients (50%), in the lower rectum in 6 patients (50%). Mean operative time was 356.5 ± 76.2 min (range 240–494). Eleven out 12 patients (91.6%) had less than 200 mL of intraoperative blood loss. Mean hospital stay was 10.9 ± 4.6 days (range 5–19). No mortality was recorded. Intraoperative complications were recorded in 1, while early post-operative complications (< 30 days) were observed in 5 patients (41.6%). Histopathology showed in all cases an intact mesorectum. Mean number of lymphnodes harvested was 13.6 ± 6.6 (range 4–29). Distal and circumferential margin was, respectively, of 20.8 ± 14.2 mm (range 2–45 mm) and 16.1 ± 7.6 mm (range 3–30 mm). The comparative analysis showed significant differences concerning mean operative time (p = 0.0473) and estimated blood loss (p = 0.0367). This study confirms this technique is safe and feasible, but more evidence to support its use over conventional laparoscopic surgery is needed.
Lingua originaleEnglish
pagine (da-a)157-163
Numero di pagine7
RivistaUpdates in Surgery
Stato di pubblicazionePubblicato - 2019
Pubblicato esternamente


  • Adenocarcinoma
  • Adult
  • Aged
  • Anal Canal
  • Animals
  • Blood Loss, Surgical
  • Digestive System Surgical Procedures
  • Female
  • Humans
  • Laparoscopy
  • Male
  • Middle Aged
  • Operative Time
  • Rectal Neoplasms
  • Rectal cancer
  • Rectum
  • TME
  • Transanal surgery
  • Treatment Outcome


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