Trabectedin as single agent in the salvage treatment of heavily treated ovarian cancer patients: a retrospective, multicenter study

Maria Gabriella Ferrandina; Vanda Salutari; Bruno Vincenzi; Marco Marinaccio; Emanuele Naglieri; Vera Loizzi; Silvia Carpano; Giulia Amadio; Giuseppe Tonini; Giovanni Scambia; Domenica Lorusso

doi:10.1016/j.ygyno.2013.06.008

Trabectedin as single agent in the salvage treatment of heavily treated ovarian cancer patients: a retrospective, multicenter study

Maria Gabriella Ferrandina
, Vanda Salutari
, Bruno Vincenzi
, Marco Marinaccio
, Emanuele Naglieri
, Vera Loizzi
, Silvia Carpano
, Giulia Amadio
, Giuseppe Tonini
, Giovanni Scambia
, Domenica Lorusso

Medical Oncology
University of Bari
IRCCS Istituto tumori Giovanni Paolo II - Bari
Research Cancer Institute
IRCCS Fondazione Istituto Nazionale per lo studio e la cura dei tumori - Milano

Risultato della ricerca: Contributo in rivista › Articolo

16 Citazioni (Scopus)

Abstract

The aim of this multicenter, retrospective study was to evaluate the efficacy and the safety of single agent Trabectedin (ET-743, Yondelis) in very heavily treated, relapsed ovarian cancer (ROC) patients.

Lingua originale	Inglese
pagine (da-a)	505-510
Numero di pagine	6
Rivista	Gynecologic Oncology
Volume	130
DOI	https://doi.org/10.1016/j.ygyno.2013.06.008
Stato di pubblicazione	Pubblicato - 2013

OSS delle Nazioni Unite

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SDG 3 Salute e benessere

Keywords

Adult
Aged
Alanine Transaminase
Antineoplastic Agents, Alkylating
Aspartate Aminotransferases
Asthenia
Carcinoma
Dioxoles
Disease-Free Survival
Drug Resistance, Neoplasm
Female
Humans
Middle Aged
Neutropenia
Ovarian Neoplasms
Ovarian cancer
Platinum Compounds
Retrospective Studies
Salvage Therapy
Salvage treatment
Tetrahydroisoquinolines
Trabectedin

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10.1016/j.ygyno.2013.06.008

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Ferrandina, M. G., Salutari, V., Vincenzi, B., Marinaccio, M., Naglieri, E., Loizzi, V., Carpano, S., Amadio, G., Tonini, G., Scambia, G., & Lorusso, D. (2013). Trabectedin as single agent in the salvage treatment of heavily treated ovarian cancer patients: a retrospective, multicenter study. Gynecologic Oncology, 130, 505-510. https://doi.org/10.1016/j.ygyno.2013.06.008

@article{d8dd30bbbf564f9a97708effc0c67baa,

title = "Trabectedin as single agent in the salvage treatment of heavily treated ovarian cancer patients: a retrospective, multicenter study",

abstract = "The aim of this multicenter, retrospective study was to evaluate the efficacy and the safety of single agent Trabectedin (ET-743, Yondelis) in very heavily treated, relapsed ovarian cancer (ROC) patients.",

keywords = "Adult, Aged, Alanine Transaminase, Antineoplastic Agents, Alkylating, Aspartate Aminotransferases, Asthenia, Carcinoma, Dioxoles, Disease-Free Survival, Drug Resistance, Neoplasm, Female, Humans, Middle Aged, Neutropenia, Ovarian Neoplasms, Ovarian cancer, Platinum Compounds, Retrospective Studies, Salvage Therapy, Salvage treatment, Tetrahydroisoquinolines, Trabectedin, Adult, Aged, Alanine Transaminase, Antineoplastic Agents, Alkylating, Aspartate Aminotransferases, Asthenia, Carcinoma, Dioxoles, Disease-Free Survival, Drug Resistance, Neoplasm, Female, Humans, Middle Aged, Neutropenia, Ovarian Neoplasms, Ovarian cancer, Platinum Compounds, Retrospective Studies, Salvage Therapy, Salvage treatment, Tetrahydroisoquinolines, Trabectedin",

author = "Ferrandina, \{Maria Gabriella\} and Vanda Salutari and Bruno Vincenzi and Marco Marinaccio and Emanuele Naglieri and Vera Loizzi and Silvia Carpano and Giulia Amadio and Giuseppe Tonini and Giovanni Scambia and Domenica Lorusso",

year = "2013",

doi = "10.1016/j.ygyno.2013.06.008",

language = "English",

volume = "130",

pages = "505--510",

journal = "Gynecologic Oncology",

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publisher = "Academic Press Inc.",

}

Ferrandina, MG, Salutari, V, Vincenzi, B, Marinaccio, M, Naglieri, E, Loizzi, V, Carpano, S, Amadio, G, Tonini, G, Scambia, G & Lorusso, D 2013, 'Trabectedin as single agent in the salvage treatment of heavily treated ovarian cancer patients: a retrospective, multicenter study', Gynecologic Oncology, vol. 130, pagg. 505-510. https://doi.org/10.1016/j.ygyno.2013.06.008

TY - JOUR

T1 - Trabectedin as single agent in the salvage treatment of heavily treated ovarian cancer patients: a retrospective, multicenter study

AU - Ferrandina, Maria Gabriella

AU - Salutari, Vanda

AU - Vincenzi, Bruno

AU - Marinaccio, Marco

AU - Naglieri, Emanuele

AU - Loizzi, Vera

AU - Carpano, Silvia

AU - Amadio, Giulia

AU - Tonini, Giuseppe

AU - Scambia, Giovanni

AU - Lorusso, Domenica

PY - 2013

Y1 - 2013

N2 - The aim of this multicenter, retrospective study was to evaluate the efficacy and the safety of single agent Trabectedin (ET-743, Yondelis) in very heavily treated, relapsed ovarian cancer (ROC) patients.

AB - The aim of this multicenter, retrospective study was to evaluate the efficacy and the safety of single agent Trabectedin (ET-743, Yondelis) in very heavily treated, relapsed ovarian cancer (ROC) patients.

KW - Adult

KW - Aged

KW - Alanine Transaminase

KW - Antineoplastic Agents, Alkylating

KW - Aspartate Aminotransferases

KW - Asthenia

KW - Carcinoma

KW - Dioxoles

KW - Disease-Free Survival

KW - Drug Resistance, Neoplasm

KW - Female

KW - Humans

KW - Middle Aged

KW - Neutropenia

KW - Ovarian Neoplasms

KW - Ovarian cancer

KW - Platinum Compounds

KW - Retrospective Studies

KW - Salvage Therapy

KW - Salvage treatment

KW - Tetrahydroisoquinolines

KW - Trabectedin

KW - Adult

KW - Aged

KW - Alanine Transaminase

KW - Antineoplastic Agents, Alkylating

KW - Aspartate Aminotransferases

KW - Asthenia

KW - Carcinoma

KW - Dioxoles

KW - Disease-Free Survival

KW - Drug Resistance, Neoplasm

KW - Female

KW - Humans

KW - Middle Aged

KW - Neutropenia

KW - Ovarian Neoplasms

KW - Ovarian cancer

KW - Platinum Compounds

KW - Retrospective Studies

KW - Salvage Therapy

KW - Salvage treatment

KW - Tetrahydroisoquinolines

KW - Trabectedin

UR - http://hdl.handle.net/10807/57126

U2 - 10.1016/j.ygyno.2013.06.008

DO - 10.1016/j.ygyno.2013.06.008

M3 - Article

SN - 1095-6859

VL - 130

SP - 505

EP - 510

JO - Gynecologic Oncology

JF - Gynecologic Oncology

ER -

Trabectedin as single agent in the salvage treatment of heavily treated ovarian cancer patients: a retrospective, multicenter study

Abstract

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Keywords

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