Topical photodynamic therapy in the treatment of benign oral mucosal lesions: A systematic review

Antonio Romano, Dario Di Stasio, Dorina Lauritano, Carlo Lajolo, Fausto Fiori, Enrica Gentile, Enzo Gentile, Alberta Lucchese

Risultato della ricerca: Contributo in rivistaArticolo in rivista

1 Citazioni (Scopus)


Background The introduction of photodynamic therapy (PDT) in various branches of the dental field such as endodontics, implantology, periodontology, and restorative dentistry and oral medicine has become useful in recent decades. This systematic review presents an overview of the literature to evaluate the usefulness of topical PDT for the treatment of benign oral soft tissue lesions and to identify limitations in prior studies to improve PDT applications.Methods We performed a review of the literature using different search engines (PubMed, ISI Web of Science, and the Cochrane Library) employing MeSH terms such as "Photodynamic therapy" and "PDT" in conjunction with other terms. We utilized the Population, Intervention, Comparison, Outcomes, and Study design (PICOS) method to define our study eligibility criteria.Results Initial results were 1513. Finally, there were only 21 studies that met our selection criteria. We divided the 21 selected items into two groups: inflammatory diseases and infective diseases.Conclusions Although topical PDT is an easy to perform and well-tolerated treatment and appears to be a valid method with promising results in the treatment of benign lesions of the oral cavity's soft tissues, further studies are needed to complete the current knowledge of this technique.
Lingua originaleEnglish
pagine (da-a)N/A-N/A
Stato di pubblicazionePubblicato - 2020


  • PDT
  • Photodynamic therapy
  • benign lesions
  • oral


Entra nei temi di ricerca di 'Topical photodynamic therapy in the treatment of benign oral mucosal lesions: A systematic review'. Insieme formano una fingerprint unica.

Cita questo