Top cardiac arrest randomised trials of 2023

In this article, we summarise the key findings from four important multicentre RCTs published in 2023: Early Initiation of Extracorporeal Life Support in Refractory OHCA (INCEPTION) trial, Targeted Therapeutic Mild Hypercapnia after Resuscitated Cardiac Arrest (TAME),A Randomized tRial of Expedited transfer to a cardiac arrest center for non-ST elevation OHCA (ARREST), and STERoid for Out-of-Hospital Cardiac Arrest (STEROHCA) trial. Articles were selected based on their large sample size, multicentre design, assessment of significant clinical outcomes, and publication in high-impact medical Journals.