Toll-like receptor 4 mediates endothelial cell activation through NF-κB but is not associated with endothelial dysfunction in patients with rheumatoid arthritis

Carmine Cardillo, Rossella Menghini, Umberto Campia, Manfredi Tesauro, Arianna Marino, Valentina Rovella, Giuseppe Rodia, Nicola Di Daniele, Massimo Federici

Risultato della ricerca: Contributo in rivistaArticolo in rivista

27 Citazioni (Scopus)


To investigate the effects of TLR4 antagonism on human endothelial cells activation and cytokine expression, and whether the Asp299Gly TLR4 polymorphism is associated with better endothelial function in patients with rheumatoid arthritis (RA).
Lingua originaleEnglish
pagine (da-a)e99053-e99053
RivistaPLoS One
Stato di pubblicazionePubblicato - 2014


  • Aorta
  • Arthritis, Rheumatoid
  • Cells, Cultured
  • Disaccharides
  • Endothelium, Vascular
  • Humans
  • Lipopolysaccharides
  • NF-kappa B
  • Phosphorylation
  • Sugar Phosphates
  • Toll-Like Receptor 4

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