Thrombopoietin serum levels in patients with inflammatory bowel disease with and without previous thromboembolic events

Alfredo Papa, Nicola Piccirillo, Giovanni Battista Gasbarrini, Antonio Gasbarrini, Silvio Danese, Antonino Grillo, Giuseppe Leone, C Toriani Terenzi, F Bartolozzi, Ac Piscaglia, N Gentiloni Silveri

Risultato della ricerca: Contributo in rivistaArticolo in rivista

17 Citazioni (Scopus)

Abstract

Patients affected by inflammatory bowel disease frequently suffer from thromboembolic complications and mesenteric microvascular occlusion could be involved in the pathogenesis of inflammatory bowel disease. Increased platelet counts and abnormal platelet function seem to play a crucial role in determining the hypercoagulable state observed in inflammatory bowel disease. Thrombopoietin is considered the primary regulator of thrombopoiesis and recent studies have investigated the role of thrombopoietin in inflammatory bowel disease. However, the available data are not conclusive. The aim of this study was to assess thrombopoietin serum levels in inflammatory bowel disease patients according to platelet counts, disease activity and previous thrombotic events.
Lingua originaleEnglish
pagine (da-a)132-135
Numero di pagine4
RivistaHepato-Gastroenterology
Volume50
Stato di pubblicazionePubblicato - 2003

Keywords

  • Aged, 80 and over
  • Colitis, Ulcerative
  • Crohn Disease
  • Middle Aged
  • Platelet Count
  • Risk Factors
  • Severity of Illness Index
  • Thromboembolism
  • Thrombopoietin

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