The viral load of Epstein-Barr virus (EBV) DNA in peripheral blood predicts for biological and clinical characteristics in Hodgkin lymphoma

Stefan Hohaus; Rosaria Santangelo; Manuela Giachelia; Barbara Vannata; Giuseppina Massini; Annarosa Cuccaro; Maurizio Martini; Valeriana Cesarini; Tonia Cenci; Francesco D'Alo'; Maria Teresa Voso; Giovanni Fadda; Giuseppe Leone; Luigi Maria Larocca

doi:10.1158/1078-0432.CCR-10-3327

The viral load of Epstein-Barr virus (EBV) DNA in peripheral blood predicts for biological and clinical characteristics in Hodgkin lymphoma

Stefan Hohaus^*
, Rosaria Santangelo
, Manuela Giachelia
, Barbara Vannata
, Giuseppina Massini
, Annarosa Cuccaro
, Maurizio Martini
, Valeriana Cesarini
, Tonia Cenci
, Francesco D'Alo'
, Maria Teresa Voso
, Giovanni Fadda
, Giuseppe Leone
, Luigi Maria Larocca

^*Autore corrispondente per questo lavoro

Risultato della ricerca: Contributo in rivista › Articolo › peer review

69 Citazioni (Scopus)

Abstract

The Epstein-Barr virus (EBV) is present in the malignant Hodgkin/Reed-Sternberg (HRS) cells of 20% to 40% cases of Hodgkin lymphoma (HL) in Western countries. We were interested in the detection and quantification of cell-free plasma EBV-DNA as an indicator of biological and clinical characteristics in EBV-associated HL.

Lingua originale	Inglese
pagine (da-a)	2885-2892
Numero di pagine	8
Rivista	Clinical Cancer Research
Volume	17
Numero di pubblicazione	9
DOI	https://doi.org/10.1158/1078-0432.CCR-10-3327
Stato di pubblicazione	Pubblicato - 2011

All Science Journal Classification (ASJC) codes

Oncologia
Ricerca sul Cancro

Keywords

Antineoplastic Combined Chemotherapy Protocols
DNA
Epstein-Barr Virus Infections
Hodgkin Disease
Viral

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10.1158/1078-0432.CCR-10-3327

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Hohaus, S., Santangelo, R., Giachelia, M., Vannata, B., Massini, G., Cuccaro, A., Martini, M., Cesarini, V., Cenci, T., D'Alo', F., Voso, M. T., Fadda, G., Leone, G., & Larocca, L. M. (2011). The viral load of Epstein-Barr virus (EBV) DNA in peripheral blood predicts for biological and clinical characteristics in Hodgkin lymphoma. Clinical Cancer Research, 17(9), 2885-2892. https://doi.org/10.1158/1078-0432.CCR-10-3327

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title = "The viral load of Epstein-Barr virus (EBV) DNA in peripheral blood predicts for biological and clinical characteristics in Hodgkin lymphoma",

abstract = "The Epstein-Barr virus (EBV) is present in the malignant Hodgkin/Reed-Sternberg (HRS) cells of 20\% to 40\% cases of Hodgkin lymphoma (HL) in Western countries. We were interested in the detection and quantification of cell-free plasma EBV-DNA as an indicator of biological and clinical characteristics in EBV-associated HL.",

keywords = "Antineoplastic Combined Chemotherapy Protocols, DNA, Epstein-Barr Virus Infections, Hodgkin Disease, Viral, Antineoplastic Combined Chemotherapy Protocols, DNA, Epstein-Barr Virus Infections, Hodgkin Disease, Viral",

author = "Stefan Hohaus and Rosaria Santangelo and Manuela Giachelia and Barbara Vannata and Giuseppina Massini and Annarosa Cuccaro and Maurizio Martini and Valeriana Cesarini and Tonia Cenci and Francesco D'Alo' and Voso, \{Maria Teresa\} and Giovanni Fadda and Giuseppe Leone and Larocca, \{Luigi Maria\}",

year = "2011",

doi = "10.1158/1078-0432.CCR-10-3327",

language = "English",

volume = "17",

pages = "2885--2892",

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Hohaus, S , Santangelo, R, Giachelia, M, Vannata, B, Massini, G, Cuccaro, A, Martini, M, Cesarini, V, Cenci, T, D'Alo', F, Voso, MT, Fadda, G, Leone, G & Larocca, LM 2011, 'The viral load of Epstein-Barr virus (EBV) DNA in peripheral blood predicts for biological and clinical characteristics in Hodgkin lymphoma', Clinical Cancer Research, vol. 17, n. 9, pagg. 2885-2892. https://doi.org/10.1158/1078-0432.CCR-10-3327

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T1 - The viral load of Epstein-Barr virus (EBV) DNA in peripheral blood predicts for biological and clinical characteristics in Hodgkin lymphoma

AU - Hohaus, Stefan

AU - Santangelo, Rosaria

AU - Giachelia, Manuela

AU - Vannata, Barbara

AU - Massini, Giuseppina

AU - Cuccaro, Annarosa

AU - Martini, Maurizio

AU - Cesarini, Valeriana

AU - Cenci, Tonia

AU - D'Alo', Francesco

AU - Voso, Maria Teresa

AU - Fadda, Giovanni

AU - Leone, Giuseppe

AU - Larocca, Luigi Maria

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AB - The Epstein-Barr virus (EBV) is present in the malignant Hodgkin/Reed-Sternberg (HRS) cells of 20% to 40% cases of Hodgkin lymphoma (HL) in Western countries. We were interested in the detection and quantification of cell-free plasma EBV-DNA as an indicator of biological and clinical characteristics in EBV-associated HL.

KW - Antineoplastic Combined Chemotherapy Protocols

KW - DNA

KW - Epstein-Barr Virus Infections

KW - Hodgkin Disease

KW - Viral

KW - Antineoplastic Combined Chemotherapy Protocols

KW - DNA

KW - Epstein-Barr Virus Infections

KW - Hodgkin Disease

KW - Viral

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The viral load of Epstein-Barr virus (EBV) DNA in peripheral blood predicts for biological and clinical characteristics in Hodgkin lymphoma

Abstract

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Keywords

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