The viral load of Epstein-Barr virus (EBV) DNA in peripheral blood predicts for biological and clinical characteristics in Hodgkin lymphoma

Stefan Hohaus; Rosaria Santangelo; Manuela Giachelia; Barbara Vannata; Giuseppina Massini; Annarosa Cuccaro; Maurizio Martini; Valeriana Cesarini; Tonia Cenci; Francesco D'Alo'; Maria Teresa Voso; Giovanni Fadda; Giuseppe Leone; Luigi Maria Larocca

doi:10.1158/1078-0432.CCR-10-3327

The viral load of Epstein-Barr virus (EBV) DNA in peripheral blood predicts for biological and clinical characteristics in Hodgkin lymphoma

Stefan Hohaus, Rosaria Santangelo, Manuela Giachelia, Barbara Vannata, Giuseppina Massini, Annarosa Cuccaro, Maurizio Martini, Valeriana Cesarini, Tonia Cenci, Francesco D'Alo', Maria Teresa Voso, Giovanni Fadda, Giuseppe Leone, Luigi Maria Larocca

Risultato della ricerca: Contributo in rivista › Articolo in rivista

Abstract

The Epstein-Barr virus (EBV) is present in the malignant Hodgkin/Reed-Sternberg (HRS) cells of 20% to 40% cases of Hodgkin lymphoma (HL) in Western countries. We were interested in the detection and quantification of cell-free plasma EBV-DNA as an indicator of biological and clinical characteristics in EBV-associated HL.

Lingua originale	English
pagine (da-a)	2885-2892
Numero di pagine	8
Rivista	Clinical Cancer Research
Volume	17
DOI	https://doi.org/10.1158/1078-0432.CCR-10-3327
Stato di pubblicazione	Pubblicato - 2011

Keywords

Adolescent
Adult
Aged
Aged, 80 and over
Antineoplastic Combined Chemotherapy Protocols
DNA, Viral
Epstein-Barr Virus Infections
Female
Herpesvirus 4, Human
Hodgkin Disease
Humans
Male
Middle Aged
Prognosis
Viral Load
Young Adult

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Hohaus, S., Santangelo, R., Giachelia, M., Vannata, B., Massini, G., Cuccaro, A., Martini, M., Cesarini, V., Cenci, T., D'Alo', F., Voso, M. T., Fadda, G., Leone, G., & Larocca, L. M. (2011). The viral load of Epstein-Barr virus (EBV) DNA in peripheral blood predicts for biological and clinical characteristics in Hodgkin lymphoma. Clinical Cancer Research, 17, 2885-2892. https://doi.org/10.1158/1078-0432.CCR-10-3327

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title = "The viral load of Epstein-Barr virus (EBV) DNA in peripheral blood predicts for biological and clinical characteristics in Hodgkin lymphoma",

abstract = "The Epstein-Barr virus (EBV) is present in the malignant Hodgkin/Reed-Sternberg (HRS) cells of 20% to 40% cases of Hodgkin lymphoma (HL) in Western countries. We were interested in the detection and quantification of cell-free plasma EBV-DNA as an indicator of biological and clinical characteristics in EBV-associated HL.",

keywords = "Adolescent, Adult, Aged, Aged, 80 and over, Antineoplastic Combined Chemotherapy Protocols, DNA, Viral, Epstein-Barr Virus Infections, Female, Herpesvirus 4, Human, Hodgkin Disease, Humans, Male, Middle Aged, Prognosis, Viral Load, Young Adult, Adolescent, Adult, Aged, Aged, 80 and over, Antineoplastic Combined Chemotherapy Protocols, DNA, Viral, Epstein-Barr Virus Infections, Female, Herpesvirus 4, Human, Hodgkin Disease, Humans, Male, Middle Aged, Prognosis, Viral Load, Young Adult",

author = "Stefan Hohaus and Rosaria Santangelo and Manuela Giachelia and Barbara Vannata and Giuseppina Massini and Annarosa Cuccaro and Maurizio Martini and Valeriana Cesarini and Tonia Cenci and Francesco D'Alo' and Voso, {Maria Teresa} and Giovanni Fadda and Giuseppe Leone and Larocca, {Luigi Maria}",

year = "2011",

doi = "10.1158/1078-0432.CCR-10-3327",

language = "English",

volume = "17",

pages = "2885--2892",

journal = "Clinical Cancer Research",

issn = "1078-0432",

publisher = "American Association for Cancer Research Inc.",

}

Hohaus, S , Santangelo, R, Giachelia, M, Vannata, B, Massini, G, Cuccaro, A, Martini, M, Cesarini, V, Cenci, T, D'Alo', F, Voso, MT, Fadda, G, Leone, G & Larocca, LM 2011, 'The viral load of Epstein-Barr virus (EBV) DNA in peripheral blood predicts for biological and clinical characteristics in Hodgkin lymphoma', Clinical Cancer Research, vol. 17, pagg. 2885-2892. https://doi.org/10.1158/1078-0432.CCR-10-3327

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T1 - The viral load of Epstein-Barr virus (EBV) DNA in peripheral blood predicts for biological and clinical characteristics in Hodgkin lymphoma

AU - Hohaus, Stefan

AU - Santangelo, Rosaria

AU - Giachelia, Manuela

AU - Vannata, Barbara

AU - Massini, Giuseppina

AU - Cuccaro, Annarosa

AU - Martini, Maurizio

AU - Cesarini, Valeriana

AU - Cenci, Tonia

AU - D'Alo', Francesco

AU - Voso, Maria Teresa

AU - Fadda, Giovanni

AU - Leone, Giuseppe

AU - Larocca, Luigi Maria

PY - 2011

Y1 - 2011

N2 - The Epstein-Barr virus (EBV) is present in the malignant Hodgkin/Reed-Sternberg (HRS) cells of 20% to 40% cases of Hodgkin lymphoma (HL) in Western countries. We were interested in the detection and quantification of cell-free plasma EBV-DNA as an indicator of biological and clinical characteristics in EBV-associated HL.

AB - The Epstein-Barr virus (EBV) is present in the malignant Hodgkin/Reed-Sternberg (HRS) cells of 20% to 40% cases of Hodgkin lymphoma (HL) in Western countries. We were interested in the detection and quantification of cell-free plasma EBV-DNA as an indicator of biological and clinical characteristics in EBV-associated HL.

KW - Adolescent

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Antineoplastic Combined Chemotherapy Protocols

KW - DNA, Viral

KW - Epstein-Barr Virus Infections

KW - Female

KW - Herpesvirus 4, Human

KW - Hodgkin Disease

KW - Humans

KW - Male

KW - Middle Aged

KW - Prognosis

KW - Viral Load

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KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Antineoplastic Combined Chemotherapy Protocols

KW - DNA, Viral

KW - Epstein-Barr Virus Infections

KW - Female

KW - Herpesvirus 4, Human

KW - Hodgkin Disease

KW - Humans

KW - Male

KW - Middle Aged

KW - Prognosis

KW - Viral Load

KW - Young Adult

UR - http://hdl.handle.net/10807/25737

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DO - 10.1158/1078-0432.CCR-10-3327

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VL - 17

SP - 2885

EP - 2892

JO - Clinical Cancer Research

JF - Clinical Cancer Research

ER -

The viral load of Epstein-Barr virus (EBV) DNA in peripheral blood predicts for biological and clinical characteristics in Hodgkin lymphoma

Abstract

Keywords

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