The viral load of Epstein-Barr virus (EBV) DNA in peripheral blood predicts for biological and clinical characteristics in Hodgkin lymphoma

Stefan Hohaus, Rosaria Santangelo, Maurizio Martini, Francesco D'Alo', Giovanni Fadda, Luigi Maria Larocca, Manuela Giachelia, Barbara Vannata, Giuseppina Massini, Annarosa Cuccaro, Tonia Cenci, Maria Teresa Voso, Giuseppe Leone, Valeriana Cesarini

Risultato della ricerca: Contributo in rivistaArticolo in rivista

Abstract

The Epstein-Barr virus (EBV) is present in the malignant Hodgkin/Reed-Sternberg (HRS) cells of 20% to 40% cases of Hodgkin lymphoma (HL) in Western countries. We were interested in the detection and quantification of cell-free plasma EBV-DNA as an indicator of biological and clinical characteristics in EBV-associated HL.
Lingua originaleEnglish
pagine (da-a)2885-2892
Numero di pagine8
RivistaClinical Cancer Research
Volume17
DOI
Stato di pubblicazionePubblicato - 2011

Keywords

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Antineoplastic Combined Chemotherapy Protocols
  • DNA, Viral
  • Epstein-Barr Virus Infections
  • Female
  • Herpesvirus 4, Human
  • Hodgkin Disease
  • Humans
  • Male
  • Middle Aged
  • Prognosis
  • Viral Load
  • Young Adult

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