The value of electrostatic potentials of the spike receptor binding and N-terminal domains in addressing transmissibility and infectivity of SARS-CoV-2 variants of concern

Stefano Pascarella; Massimo Ciccozzi; Martina Bianchi; Domenico Benvenuto; Roberto Cauda; Antonio Cassone

doi:10.1016/j.jinf.2022.02.023

The value of electrostatic potentials of the spike receptor binding and N-terminal domains in addressing transmissibility and infectivity of SARS-CoV-2 variants of concern

Stefano Pascarella, Massimo Ciccozzi, Martina Bianchi, Domenico Benvenuto, Roberto Cauda, Antonio Cassone

Risultato della ricerca: Contributo in rivista › Articolo

Abstract

Comparison of the surface electrostatic potential of the N-terminal (NTD) and the Receptor Binding Domains (RBD) of the Wuhan and Omicron Spikes. The entire Spikes are represented with transparent ribbon models. Only the NTD and RBD surfaces of the chain A are represented. Domain net charges are reported within parenthesis beside the domain labels. Surface color ranges from -5.0 (red) to + 5.0 (blue) kT/e. Image, graphical abstract

Lingua originale	Inglese
pagine (da-a)	N/A-N/A
Rivista	Journal of Infection
DOI	https://doi.org/10.1016/j.jinf.2022.02.023
Stato di pubblicazione	Pubblicato - 2022

Keywords

covid 19

Accesso al documento

10.1016/j.jinf.2022.02.023

Altri file e collegamenti

Link a IRIS PubliCatt

Cita questo

@article{71e2e57b536f427da77f3c01831274ce,

title = "The value of electrostatic potentials of the spike receptor binding and N-terminal domains in addressing transmissibility and infectivity of SARS-CoV-2 variants of concern",

abstract = "Comparison of the surface electrostatic potential of the N-terminal (NTD) and the Receptor Binding Domains (RBD) of the Wuhan and Omicron Spikes. The entire Spikes are represented with transparent ribbon models. Only the NTD and RBD surfaces of the chain A are represented. Domain net charges are reported within parenthesis beside the domain labels. Surface color ranges from -5.0 (red) to + 5.0 (blue) kT/e. Image, graphical abstract",

keywords = "covid 19, covid 19",

author = "Stefano Pascarella and Massimo Ciccozzi and Martina Bianchi and Domenico Benvenuto and Roberto Cauda and Antonio Cassone",

year = "2022",

doi = "10.1016/j.jinf.2022.02.023",

language = "English",

pages = "N/A--N/A",

journal = "Journal of Infection",

issn = "0163-4453",

publisher = "W.B. Saunders Ltd",

}

TY - JOUR

T1 - The value of electrostatic potentials of the spike receptor binding and N-terminal domains in addressing transmissibility and infectivity of SARS-CoV-2 variants of concern

AU - Pascarella, Stefano

AU - Ciccozzi, Massimo

AU - Bianchi, Martina

AU - Benvenuto, Domenico

AU - Cauda, Roberto

AU - Cassone, Antonio

PY - 2022

Y1 - 2022

N2 - Comparison of the surface electrostatic potential of the N-terminal (NTD) and the Receptor Binding Domains (RBD) of the Wuhan and Omicron Spikes. The entire Spikes are represented with transparent ribbon models. Only the NTD and RBD surfaces of the chain A are represented. Domain net charges are reported within parenthesis beside the domain labels. Surface color ranges from -5.0 (red) to + 5.0 (blue) kT/e. Image, graphical abstract

AB - Comparison of the surface electrostatic potential of the N-terminal (NTD) and the Receptor Binding Domains (RBD) of the Wuhan and Omicron Spikes. The entire Spikes are represented with transparent ribbon models. Only the NTD and RBD surfaces of the chain A are represented. Domain net charges are reported within parenthesis beside the domain labels. Surface color ranges from -5.0 (red) to + 5.0 (blue) kT/e. Image, graphical abstract

KW - covid 19

UR - http://hdl.handle.net/10807/201603

U2 - 10.1016/j.jinf.2022.02.023

DO - 10.1016/j.jinf.2022.02.023

M3 - Article

SN - 0163-4453

SP - N/A-N/A

JO - Journal of Infection

JF - Journal of Infection

ER -

The value of electrostatic potentials of the spike receptor binding and N-terminal domains in addressing transmissibility and infectivity of SARS-CoV-2 variants of concern

Abstract

Keywords

Accesso al documento

Altri file e collegamenti

Fingerprint

Cita questo