The use of the OMERACT ultrasound tenosynovitis scoring system in multicenter clinical trials

Maria Antonietta D'Agostino; Mads Ammitzbøll-Danielsen; Mikkel Østergaard; Esperanza Naredo; Annamaria Iagnocco; Ingrid Möller; Maria-Antonietta D'Agostino; Frédérique Gandjbakhch; Lene Terslev

doi:10.3899/jrheum.170501

The use of the OMERACT ultrasound tenosynovitis scoring system in multicenter clinical trials

Maria Antonietta D'Agostino, Mads Ammitzbøll-Danielsen, Mikkel Østergaard, Esperanza Naredo, Annamaria Iagnocco, Ingrid Möller, Maria-Antonietta D'Agostino, Frédérique Gandjbakhch, Lene Terslev

Risultato della ricerca: Contributo in rivista › Articolo in rivista

3 Citazioni (Scopus)

Abstract

Objective: To test the sensitivity to change of the Outcome Measures in Rheumatology Clinical Trials (OMERACT) ultrasound (US) scoring system for tenosynovitis when applied in a multicenter design. Methods: RA patients with US-verified tenosynovitis were recruited when scheduled for treatment intensification. Tenosynovitis was assessed at baseline, and 3 and 6 months followup, using the semiquantitative OMERACT scoring system. Results: Expressed in median (25th; 75th percentiles), the overall greyscale and Doppler score decreased significantly from baseline at 4 (2; 7) and 3 (2; 6), to 6 months at 2 (0; 3) and 0 (0; 1, p < 0.01), respectively, and showed high responsiveness (standardized response mean = 0.8). Conclusion: The OMERACT US scoring system for tenosynovitis showed high responsiveness, supporting its use for diagnosing and monitoring tenosynovitis in multicenter trials.

Lingua originale	English
pagine (da-a)	165-169
Numero di pagine	5
Rivista	THE JOURNAL OF RHEUMATOLOGY
Volume	45
DOI	https://doi.org/10.3899/jrheum.170501
Stato di pubblicazione	Pubblicato - 2018

Keywords

Adult
Aged
Arthritis, Rheumatoid
C-Reactive Protein
Female
Follow-Up Studies
Health Surveys
Humans
Male
Middle Aged
Omeract
Outpatients
Pain Measurement
Research Design
Rheumatoid arthritis
Statistics, Nonparametric
Synovitis
Tenosynovitis
Ultrasonography
Ultrasonography, Doppler

Accesso al documento

10.3899/jrheum.170501

Altri file e collegamenti

Link a IRIS PubliCatt

Fingerprint Entra nei temi di ricerca di 'The use of the OMERACT ultrasound tenosynovitis scoring system in multicenter clinical trials'. Insieme formano una fingerprint unica.

Cita questo

D'Agostino, Maria Antonietta ; Ammitzbøll-Danielsen, Mads ; Østergaard, Mikkel ; Naredo, Esperanza ; Iagnocco, Annamaria ; Möller, Ingrid ; D'Agostino, Maria-Antonietta ; Gandjbakhch, Frédérique ; Terslev, Lene. / The use of the OMERACT ultrasound tenosynovitis scoring system in multicenter clinical trials. In: THE JOURNAL OF RHEUMATOLOGY. 2018 ; Vol. 45. pagg. 165-169.

@article{93c8db8e9d494ba89afa8497da53638a,

title = "The use of the OMERACT ultrasound tenosynovitis scoring system in multicenter clinical trials",

abstract = "Objective: To test the sensitivity to change of the Outcome Measures in Rheumatology Clinical Trials (OMERACT) ultrasound (US) scoring system for tenosynovitis when applied in a multicenter design. Methods: RA patients with US-verified tenosynovitis were recruited when scheduled for treatment intensification. Tenosynovitis was assessed at baseline, and 3 and 6 months followup, using the semiquantitative OMERACT scoring system. Results: Expressed in median (25th; 75th percentiles), the overall greyscale and Doppler score decreased significantly from baseline at 4 (2; 7) and 3 (2; 6), to 6 months at 2 (0; 3) and 0 (0; 1, p < 0.01), respectively, and showed high responsiveness (standardized response mean = 0.8). Conclusion: The OMERACT US scoring system for tenosynovitis showed high responsiveness, supporting its use for diagnosing and monitoring tenosynovitis in multicenter trials.",

keywords = "Adult, Aged, Arthritis, Rheumatoid, C-Reactive Protein, Female, Follow-Up Studies, Health Surveys, Humans, Male, Middle Aged, Omeract, Outpatients, Pain Measurement, Research Design, Rheumatoid arthritis, Statistics, Nonparametric, Synovitis, Tenosynovitis, Ultrasonography, Ultrasonography, Doppler, Adult, Aged, Arthritis, Rheumatoid, C-Reactive Protein, Female, Follow-Up Studies, Health Surveys, Humans, Male, Middle Aged, Omeract, Outpatients, Pain Measurement, Research Design, Rheumatoid arthritis, Statistics, Nonparametric, Synovitis, Tenosynovitis, Ultrasonography, Ultrasonography, Doppler",

author = "D'Agostino, {Maria Antonietta} and Mads Ammitzb{\o}ll-Danielsen and Mikkel {\O}stergaard and Esperanza Naredo and Annamaria Iagnocco and Ingrid M{\"o}ller and Maria-Antonietta D'Agostino and Fr{\'e}d{\'e}rique Gandjbakhch and Lene Terslev",

year = "2018",

doi = "10.3899/jrheum.170501",

language = "English",

volume = "45",

pages = "165--169",

journal = "Journal of Rheumatology",

issn = "0315-162X",

publisher = "Journal of Rheumatology:920 Yonge Street, Suite 115, Toronto Ontario M4W 3C7 Canada:(416)967-5155, EMAIL: jrheum@inforamp.com, INTERNET: http://jrheum.com, Fax: (416)967-7556",

}

The use of the OMERACT ultrasound tenosynovitis scoring system in multicenter clinical trials. / D'Agostino, Maria Antonietta; Ammitzbøll-Danielsen, Mads; Østergaard, Mikkel; Naredo, Esperanza; Iagnocco, Annamaria; Möller, Ingrid; D'Agostino, Maria-Antonietta; Gandjbakhch, Frédérique; Terslev, Lene.

In: THE JOURNAL OF RHEUMATOLOGY, Vol. 45, 2018, pag. 165-169.

Risultato della ricerca: Contributo in rivista › Articolo in rivista

TY - JOUR

T1 - The use of the OMERACT ultrasound tenosynovitis scoring system in multicenter clinical trials

AU - D'Agostino, Maria Antonietta

AU - Ammitzbøll-Danielsen, Mads

AU - Østergaard, Mikkel

AU - Naredo, Esperanza

AU - Iagnocco, Annamaria

AU - Möller, Ingrid

AU - D'Agostino, Maria-Antonietta

AU - Gandjbakhch, Frédérique

AU - Terslev, Lene

PY - 2018

Y1 - 2018

N2 - Objective: To test the sensitivity to change of the Outcome Measures in Rheumatology Clinical Trials (OMERACT) ultrasound (US) scoring system for tenosynovitis when applied in a multicenter design. Methods: RA patients with US-verified tenosynovitis were recruited when scheduled for treatment intensification. Tenosynovitis was assessed at baseline, and 3 and 6 months followup, using the semiquantitative OMERACT scoring system. Results: Expressed in median (25th; 75th percentiles), the overall greyscale and Doppler score decreased significantly from baseline at 4 (2; 7) and 3 (2; 6), to 6 months at 2 (0; 3) and 0 (0; 1, p < 0.01), respectively, and showed high responsiveness (standardized response mean = 0.8). Conclusion: The OMERACT US scoring system for tenosynovitis showed high responsiveness, supporting its use for diagnosing and monitoring tenosynovitis in multicenter trials.

AB - Objective: To test the sensitivity to change of the Outcome Measures in Rheumatology Clinical Trials (OMERACT) ultrasound (US) scoring system for tenosynovitis when applied in a multicenter design. Methods: RA patients with US-verified tenosynovitis were recruited when scheduled for treatment intensification. Tenosynovitis was assessed at baseline, and 3 and 6 months followup, using the semiquantitative OMERACT scoring system. Results: Expressed in median (25th; 75th percentiles), the overall greyscale and Doppler score decreased significantly from baseline at 4 (2; 7) and 3 (2; 6), to 6 months at 2 (0; 3) and 0 (0; 1, p < 0.01), respectively, and showed high responsiveness (standardized response mean = 0.8). Conclusion: The OMERACT US scoring system for tenosynovitis showed high responsiveness, supporting its use for diagnosing and monitoring tenosynovitis in multicenter trials.

KW - Adult

KW - Aged

KW - Arthritis, Rheumatoid

KW - C-Reactive Protein

KW - Female

KW - Follow-Up Studies

KW - Health Surveys

KW - Humans

KW - Male

KW - Middle Aged

KW - Omeract

KW - Outpatients

KW - Pain Measurement

KW - Research Design

KW - Rheumatoid arthritis

KW - Statistics, Nonparametric

KW - Synovitis

KW - Tenosynovitis

KW - Ultrasonography

KW - Ultrasonography, Doppler

KW - Adult

KW - Aged

KW - Arthritis, Rheumatoid

KW - C-Reactive Protein

KW - Female

KW - Follow-Up Studies

KW - Health Surveys

KW - Humans

KW - Male

KW - Middle Aged

KW - Omeract

KW - Outpatients

KW - Pain Measurement

KW - Research Design

KW - Rheumatoid arthritis

KW - Statistics, Nonparametric

KW - Synovitis

KW - Tenosynovitis

KW - Ultrasonography

KW - Ultrasonography, Doppler

UR - http://hdl.handle.net/10807/168587

U2 - 10.3899/jrheum.170501

DO - 10.3899/jrheum.170501

M3 - Article

VL - 45

SP - 165

EP - 169

JO - Journal of Rheumatology

JF - Journal of Rheumatology

SN - 0315-162X

ER -