THE USE OF CAPILLARY ELECTROPHORESIS FOR THE DETERMINATION OF HEMOGLOBIN-VARIANTS

Massimo Castagnola, Loredana Cassiano, Diana Valeria Rossetti, Bruno Giardina, I Messana, R Rabino

Risultato della ricerca: Contributo in rivistaArticolo in rivista

30 Citazioni (Scopus)

Abstract

The application of capillary electrophoresis and related techniques for the detection of hemoglobin variants is described. Capillary zone electrophoresis (CZE) was applied for the analysis of intact tetrameric hemoglobin. CZE under denaturing conditions was used for the separation of globin chains. Both CZE and micellar electrokinetic capillary chromatography were applied for a fast and sensitive separation of tryptic digests and for the analysis of amino acid derivatives.
Lingua originaleEnglish
pagine (da-a)1492-1498
Numero di pagine7
RivistaElectrophoresis
Volume16
DOI
Stato di pubblicazionePubblicato - 1995

Keywords

  • ELECTROPHORESIS

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