TY - JOUR
T1 - The Unexpected Evolution of an Expected Complication: Hemophagocytic Lymphohistiocytosis
AU - Agnes, Annamaria
AU - Callari, Cosimo
AU - Raffaelli, Marco
PY - 2017
Y1 - 2017
N2 - Severe obesity is associated with consistent morbidity and mortality. Bariatric surgery is presently the most effective treatment for this condition, and laparoscopic Rouxen-Y gastric bypass (RYGB) is the most common surgical procedure performed. RYGB carries a mortality risk of 0.5–1.9%. One fearedearly surgical complications is postoperative leak,occurringin2.1–5.2% of patients and having a mortality rate up to 50%. Hemophagocytic lymphohistiocytosis (HLH) is a rare disease, characterized by an uncontrolled inflammatory response that leads to systemic compromise and in the end to death by multi-organ failure, bleeding, sepsis, or disseminated intravascular coagulation (DIC). We report the first case of HLH associated with complicated bariatric surgery, investigating possible reasons for this association
AB - Severe obesity is associated with consistent morbidity and mortality. Bariatric surgery is presently the most effective treatment for this condition, and laparoscopic Rouxen-Y gastric bypass (RYGB) is the most common surgical procedure performed. RYGB carries a mortality risk of 0.5–1.9%. One fearedearly surgical complications is postoperative leak,occurringin2.1–5.2% of patients and having a mortality rate up to 50%. Hemophagocytic lymphohistiocytosis (HLH) is a rare disease, characterized by an uncontrolled inflammatory response that leads to systemic compromise and in the end to death by multi-organ failure, bleeding, sepsis, or disseminated intravascular coagulation (DIC). We report the first case of HLH associated with complicated bariatric surgery, investigating possible reasons for this association
KW - Endocrinology, Diabetes and Metabolism
KW - Nutrition and Dietetics
KW - Surgery
KW - Endocrinology, Diabetes and Metabolism
KW - Nutrition and Dietetics
KW - Surgery
UR - http://hdl.handle.net/10807/101522
UR - http://www.obesitysurgery.com
U2 - 10.1007/s11695-016-2430-7
DO - 10.1007/s11695-016-2430-7
M3 - Article
SN - 0960-8923
VL - 27
SP - 205
EP - 207
JO - Obesity Surgery
JF - Obesity Surgery
ER -