The TRPM7 channel kinase: rekindling an old flame or not?

Valentina Trapani, Federica Wolf Minotti

Risultato della ricerca: Contributo in rivistaEditoriale in rivista / quotidiano

3 Citazioni (Scopus)


Far from being an accidental evolutional step, the fusion of a channel pore with a kinase domain within the TRPM7 molecule represents an optimized and integrated unit, able to couple extracellular sensing to intracellular signalling. The article by Rios et al. strongly implicates both TRPM7 kinase and Mg2+ homeostasis in cardiovascular health, but before these findings may achieve translational relevance, it is imperative to dissect all the underlying molecular mysteries.
Lingua originaleEnglish
pagine (da-a)476-478
Numero di pagine3
RivistaCardiovascular Research
Stato di pubblicazionePubblicato - 2019


  • TRPM7, inflammation, cardiovascular function


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