The Role of the Stem Cells Therapy in the Peripheral Artery Disease.

Andrea Flex, Federico Biscetti, Elisabetta Nardella, Andrea Leonardo Cecchini, Raffaele Landolfi, N Bonadia

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

2 Citazioni (Scopus)

Abstract

Vascular complications of diabetes mellitus are an important issue for all clinicians involved in the management of this complex pathology. Although many therapeutic advances have been reached, peripheral arterial disease is still an unsolved problem that each year compromises the quality of life and life span of affected patients. Oftentimes, patients, after ineffective attempts of revascularization, undergo greater amputations. At the moment, there is no effective and definitive treatment available. In this scenario, the therapeutic use of stem cells could be an interesting option. The aim of the present review is to gather all the best available evidence in this regard and to define a new role of the stem cells therapy in this field, from biomarker to possible therapeutic target.
Lingua originaleEnglish
pagine (da-a)2233-2244
Numero di pagine12
RivistaInternational Journal of Molecular Sciences
Volume2019
DOI
Stato di pubblicazionePubblicato - 2019

Keywords

  • Stem cells therapy
  • lower limb peripheral artery disease
  • type 2 diabetes mellitus

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