TY - JOUR
T1 - The role of diet on the clinical pharmacology of oral antineoplastic agents
AU - Ruggiero, Antonio
AU - Cefalo, Maria Giuseppina
AU - Coccia, Paola
AU - Mastrangelo, Stefano
AU - Maurizi, Palma
AU - Riccardi, Riccardo
PY - 2012
Y1 - 2012
N2 - The number of oral anticancer agents has greatly increased in recent years. It is a well-known fact that food intake can induce significant variations in the bioavailability of these drugs. The aim of this review is to describe the interactions between diet and oral anticancer drugs in terms of the possible effects of such interactions on reducing the antineoplastic activity of the drug or increasing its side effects.
AB - The number of oral anticancer agents has greatly increased in recent years. It is a well-known fact that food intake can induce significant variations in the bioavailability of these drugs. The aim of this review is to describe the interactions between diet and oral anticancer drugs in terms of the possible effects of such interactions on reducing the antineoplastic activity of the drug or increasing its side effects.
KW - Administration, Oral
KW - Antineoplastic Agents
KW - Biological Availability
KW - Diet
KW - Food-Drug Interactions
KW - Humans
KW - Neoplasms
KW - Administration, Oral
KW - Antineoplastic Agents
KW - Biological Availability
KW - Diet
KW - Food-Drug Interactions
KW - Humans
KW - Neoplasms
UR - http://hdl.handle.net/10807/30707
U2 - 10.1007/s00228-011-1102-8
DO - 10.1007/s00228-011-1102-8
M3 - Article
SN - 0031-6970
VL - 68
SP - 115
EP - 122
JO - European Journal of Clinical Pharmacology
JF - European Journal of Clinical Pharmacology
ER -