TY - JOUR
T1 - The Role of CD56 in Thyroid Fine Needle Aspiration Cytology: A Pilot Study Performed on Liquid Based Cytology
AU - Bizzarro, Tommaso
AU - Martini, Maurizio
AU - Marrocco, C
AU - D'Amato, D
AU - Traini, Emanuela
AU - Lombardi, Celestino Pio
AU - Pontecorvi, Alfredo
AU - Fadda, Guido
AU - Larocca, Luigi Maria
AU - Rossi, Esther
PY - 2015
Y1 - 2015
N2 - Fine needle aspiration Cytology (FNAC) fulfills a reliable role in the evaluation of thyroid lesions. Although the majority of nodules are quite easily diagnosed as benign or malignant, 30% of them represent an indeterminate category whereby the application of ancillary techniques (i.e. immunocytochemistry-ICC and molecular testing) has been encouraged. The search for a specific immunomarker of malignancy sheds light on a huge number of ICC stains although none of them attempt to yield 100% conclusive results. Our aim was to define in a pilot study on thyroid FNAC whether CD56 might be a valid marker also in comparison with HBME-1 and Galectin-3.
AB - Fine needle aspiration Cytology (FNAC) fulfills a reliable role in the evaluation of thyroid lesions. Although the majority of nodules are quite easily diagnosed as benign or malignant, 30% of them represent an indeterminate category whereby the application of ancillary techniques (i.e. immunocytochemistry-ICC and molecular testing) has been encouraged. The search for a specific immunomarker of malignancy sheds light on a huge number of ICC stains although none of them attempt to yield 100% conclusive results. Our aim was to define in a pilot study on thyroid FNAC whether CD56 might be a valid marker also in comparison with HBME-1 and Galectin-3.
KW - Fine Needle Aspiration
KW - Fine Needle Aspiration
UR - https://publicatt.unicatt.it/handle/10807/70155
UR - https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=84940861807&origin=inward
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84940861807&origin=inward
U2 - 10.1371/journal.pone.0132939
DO - 10.1371/journal.pone.0132939
M3 - Article
SN - 1932-6203
VL - 10
SP - e0132939-e0132939
JO - PLoS One
JF - PLoS One
IS - 7
ER -