The Role of CD56 in Thyroid Fine Needle Aspiration Cytology: A Pilot Study Performed on Liquid Based Cytology

Tommaso Bizzarro, Maurizio Martini, Carla Marrocco, Donato D'Amato, Emanuela Traini, Celestino Pio Lombardi, Alfredo Pontecorvi, Guido Fadda, Luigi Maria Larocca, Esther Rossi

Risultato della ricerca: Contributo in rivistaArticolo in rivista

12 Citazioni (Scopus)

Abstract

Fine needle aspiration Cytology (FNAC) fulfills a reliable role in the evaluation of thyroid lesions. Although the majority of nodules are quite easily diagnosed as benign or malignant, 30% of them represent an indeterminate category whereby the application of ancillary techniques (i.e. immunocytochemistry-ICC and molecular testing) has been encouraged. The search for a specific immunomarker of malignancy sheds light on a huge number of ICC stains although none of them attempt to yield 100% conclusive results. Our aim was to define in a pilot study on thyroid FNAC whether CD56 might be a valid marker also in comparison with HBME-1 and Galectin-3.
Lingua originaleEnglish
pagine (da-a)e0132939-e0132939
RivistaPLoS One
Volume10
DOI
Stato di pubblicazionePubblicato - 2015

Keywords

  • Fine Needle Aspiration

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