TY - JOUR
T1 - The role for high flow nasal cannula as a respiratory support strategy in adults: a clinical practice guideline
AU - Rochwerg, Bram
AU - Einav, Sharon
AU - Chaudhuri, Dipayan
AU - Mancebo, Jordi
AU - Mauri, Tommaso
AU - Helviz, Yigal
AU - Goligher, Ewan C.
AU - Jaber, Samir
AU - Ricard, Jean-Damien
AU - Rittayamai, Nuttapol
AU - Roca, Oriol
AU - Antonelli, Massimo
AU - Maggiore, Salvatore Maurizio
AU - Demoule, Alexandre
AU - Hodgson, Carol L.
AU - Mercat, Alain
AU - Wilcox, M. Elizabeth
AU - Granton, David
AU - Wang, Dominic
AU - Azoulay, Elie
AU - Ouanes-Besbes, Lamia
AU - Cinnella, Gilda
AU - Rauseo, Michela
AU - Carvalho, Carlos
AU - Dessap-Mekontso, Armand
AU - Fraser, John
AU - Frat, Jean-Pierre
AU - Gomersall, Charles
AU - Grasselli, Giacomo
AU - Hernandez, Gonzalo
AU - Jog, Sameer
AU - Pesenti, Antonio
AU - Riviello, Elisabeth D.
AU - Slutsky, Arthur S.
AU - Stapleton, Renee D.
AU - Talmor, Daniel
AU - Thille, Arnaud W.
AU - Brochard, Laurent
AU - Burns, Karen E. A.
PY - 2020
Y1 - 2020
N2 - Purpose: High flow nasal cannula (HFNC) is a relatively recent respiratory support technique which delivers high flow, heated and humidified controlled concentration of oxygen via the nasal route. Recently, its use has increased for a variety of clinical indications. To guide clinical practice, we developed evidence-based recommendations regarding use of HFNC in various clinical settings.
Methods: We formed a guideline panel composed of clinicians, methodologists and experts in respiratory medicine. Using GRADE, the panel developed recommendations for four actionable questions.
Results: The guideline panel made a strong recommendation for HFNC in hypoxemic respiratory failure compared to conventional oxygen therapy (COT) (moderate certainty), a conditional recommendation for HFNC following extubation (moderate certainty), no recommendation regarding HFNC in the peri-intubation period (moderate certainty), and a conditional recommendation for postoperative HFNC in high risk and/or obese patients following cardiac or thoracic surgery (moderate certainty).
Conclusions: This clinical practice guideline synthesizes current best-evidence into four recommendations for HFNC use in patients with hypoxemic respiratory failure, following extubation, in the peri-intubation period, and postoperatively for bedside clinicians.
AB - Purpose: High flow nasal cannula (HFNC) is a relatively recent respiratory support technique which delivers high flow, heated and humidified controlled concentration of oxygen via the nasal route. Recently, its use has increased for a variety of clinical indications. To guide clinical practice, we developed evidence-based recommendations regarding use of HFNC in various clinical settings.
Methods: We formed a guideline panel composed of clinicians, methodologists and experts in respiratory medicine. Using GRADE, the panel developed recommendations for four actionable questions.
Results: The guideline panel made a strong recommendation for HFNC in hypoxemic respiratory failure compared to conventional oxygen therapy (COT) (moderate certainty), a conditional recommendation for HFNC following extubation (moderate certainty), no recommendation regarding HFNC in the peri-intubation period (moderate certainty), and a conditional recommendation for postoperative HFNC in high risk and/or obese patients following cardiac or thoracic surgery (moderate certainty).
Conclusions: This clinical practice guideline synthesizes current best-evidence into four recommendations for HFNC use in patients with hypoxemic respiratory failure, following extubation, in the peri-intubation period, and postoperatively for bedside clinicians.
KW - Extubation
KW - High flow nasal cannula
KW - Mortality
KW - Peri-intubation
KW - Postoperative
KW - Respiratory failure
KW - Extubation
KW - High flow nasal cannula
KW - Mortality
KW - Peri-intubation
KW - Postoperative
KW - Respiratory failure
UR - http://hdl.handle.net/10807/166310
U2 - 10.1007/s00134-020-06312-y
DO - 10.1007/s00134-020-06312-y
M3 - Meeting Abstract
SN - 0342-4642
SP - 2226
EP - 2237
JO - Intensive Care Medicine
JF - Intensive Care Medicine
ER -