The recovery of platelet cyclooxygenase activity explains interindividual variability in responsiveness to low-dose aspirin in patients with and without diabetes

Bianca Rocca, Dario Pitocco, Giovanna Petrucci, Carmine Cardillo, Massimiliano Mirabella, Federico Santilli, Luciana Mucci, Francesco Zaccardi, Francesca Martini, Roberta Morosetti, Giovanni Ghirlanda, Carlo Patrono, E Vitacolonna, S Lattanzio, D Mattoscio, R Liani, N Vazzana, A Del Ponte, E Ferrante, G Davì

Risultato della ricerca: Contributo in rivistaArticolo in rivista

174 Citazioni (Scopus)

Abstract

Interindividual variability in response to aspirin has been popularized as 'resistance'. We hypothesized that faster recovery of platelet cyclooxygenase-1 activity may explain incomplete thromboxane (TX) inhibition during the 24-h dosing interval.
Lingua originaleEnglish
pagine (da-a)1220-1230
Numero di pagine11
RivistaJournal of Thrombosis and Haemostasis
Volume10
DOI
Stato di pubblicazionePubblicato - 2012

Keywords

  • aspirin
  • cyclooxygenase
  • low-dose

Fingerprint Entra nei temi di ricerca di 'The recovery of platelet cyclooxygenase activity explains interindividual variability in responsiveness to low-dose aspirin in patients with and without diabetes'. Insieme formano una fingerprint unica.

Cita questo