The practical management of chronic constipation as detected by a survey conducted on Italian gastroenterologists

Carlo Fabbri, Cristiano Spada, Salvatore E. Aragona, Giorgio Ciprandi, Guido Ciprandi, Guido Alberico, Sara Antoniazzi, Arrigo Arrigoni, Marco Astegiano, Silvia Astretto, Stefania Baroni, Edda Battaglia, Claudio Belcari, Paolo Beretta, Mario Bianchetti, Maddalena Bianchetti, Maria L. Bianchi, Barbara Bindi, Carmelo Buda, Salvatore CamilleriStefania Caronna, Giuseppe Cautela, Flaminia Cavallaro, Fabio Cavallaro, Andrea Cocco, Raffaele Colucci, Danilo Consalvo, Gabriella Cordone, Claudio Cortelezzi, Giovanni Cozzoli, Enrico A. Currò, Alberto Damiani, Andrea Damiani, Fabio D'Amore, Pasquale De Falco, Vincenzo De Girolamo, Maria Vittoria De Girolamo, Luca De Luca, Ferdinando Di Lorenzo, Sabato Di Marzo, Giovanni Di Nardo, Marco Ferrara, Roberto Fiaccavento, Daniele Fina, Rosario Frasca, Monica Gallo, Nicola Gennarelli, Giorgia Ghittoni, Francesco Giangregorio, Aurora Giannetti, Lucio A. Giglio, Simone Giuncato, Stefano Grosso, Donato Iannuzziello, Ivan Ibba, Salvatore Incarbone, Stefano La Spada, Pavlos Lagoussis, Giuseppina Lecca, Giuseppe Leonardi, Gaspare Licari, Maria Lucia, Mothanje Barbara Patricia Lucia, Guido Lupinacci, Salvatore Magri, Massimo Oppezzi, Primaldo Paiano, Vincenzo Palombo, Davide Pardocchi, Andrea Parodi, Antonino Pati, Chiara Petrini, Antonio Pinto, Paolo Pirrotta, Aniello Piscopo, Natale Polimeni, Paoletta Preatoni, Domenico Quintigliano, Elisa Radice, Giovanni Ricco, Luca Rodella, Luigi Fabrizio Rodella, Mario Schettino, Pietro Schettino, Paola Schettino, Angelo A. Schicchi, Luigi Schiffino, Carola Severi, Emanuele Sinagra, Marco Tarantello, Giorgio Valeri, Giovanni Valeri, Riccardo Vanni, Maurizio Vinti, Claudio Zulli

Risultato della ricerca: Contributo in rivistaArticolo in rivista

Abstract

BACKGROUND: Chronic constipation represents a widespread medical condition, mainly in elderly people. The management is compelling as these patients frequently have comorbidity and polypharmacy. Polyethylene glycol (PEG) is commonly used but does not resolve some complaints, mainly concerning pain and bloating. Therefore, a new medical device containing PEG plus simethicone, an antifoaming agent, has been developed. The present survey explored its use in clinical practice. METHODS: A group of 64 Italian gastroenterologists visited 2426 patients with chronic primary constipation. In about two/third, gastroenterologists freely prescribed the new medical device, and in the remaining patients, other treatments were freely chosen by doctors. Patients were followed up for three months. The number of evacuations, stool characteristics, patients’ perception of illness assessed by VAS, frequency of patients with pain and intestinal symptoms, and discontinuing patients was observed during the experience. RESULTS: The new medical device was significantly better than other therapies in improving all parameters (P<0.05 for all parameters). CONCLUSIONS: The present survey demonstrated that a new medical device containing PEG plus simethicone represents a favorable option in managing patients with chronic primary constipation as significantly and safely improves intestinal transit, reduces stool consistency, reduces symptom severity, and is highly satisfactory.
Lingua originaleEnglish
pagine (da-a)279-284
Numero di pagine6
RivistaGAZZETTA MEDICA ITALIANA. ARCHIVIO PER LE SCIENZE MEDICHE
Volume182
DOI
Stato di pubblicazionePubblicato - 2023

Keywords

  • Constipation
  • Simethicone
  • Polyethylene glycols
  • Gastroenterologists

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