THE MULTIPLE FUNCTIONS OF HEMOGLOBIN

Roberto Scatena, Bruno Giardina, Massimo Castagnola, I Messana

Risultato della ricerca: Contributo in rivistaArticolo in rivista

144 Citazioni (Scopus)

Abstract

The aim of this review is to focus and discuss several parallel biological functions of hemoglobin besides its basic function of oxygen transport. In light of the information present in the literature the following possible physiological roles of hemoglobin are discussed: (1) hemoglobin as molecular heat transducer through its oxygenation-deoxygenation cycle, (2) hemoglobin as modulator of erythrocyte metabolism, (3) hemoglobin oxidation as an onset of erythrocyte senescence, (4) hemoglobin and its implication in genetic resistance to malaria, (5) enzymatic activities of hemoglobin and interactions with drugs, and (6) hemoglobin as source of physiological active catabolites.
Lingua originaleEnglish
pagine (da-a)165-196
Numero di pagine32
RivistaCritical Reviews in Biochemistry and Molecular Biology
Volume30
DOI
Stato di pubblicazionePubblicato - 1995

Keywords

  • HEMOGLOBIN

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