THE MULTIPLE FUNCTIONS OF HEMOGLOBIN

Bruno Giardina; I Messana; Roberto Scatena; Massimo Castagnola

doi:10.3109/10409239509085142

THE MULTIPLE FUNCTIONS OF HEMOGLOBIN

Bruno Giardina, I Messana, Roberto Scatena, Massimo Castagnola

Università Cattolica del Sacro Cuore

Risultato della ricerca: Contributo in rivista › Articolo in rivista

145 Citazioni (Scopus)

Abstract

The aim of this review is to focus and discuss several parallel biological functions of hemoglobin besides its basic function of oxygen transport. In light of the information present in the literature the following possible physiological roles of hemoglobin are discussed: (1) hemoglobin as molecular heat transducer through its oxygenation-deoxygenation cycle, (2) hemoglobin as modulator of erythrocyte metabolism, (3) hemoglobin oxidation as an onset of erythrocyte senescence, (4) hemoglobin and its implication in genetic resistance to malaria, (5) enzymatic activities of hemoglobin and interactions with drugs, and (6) hemoglobin as source of physiological active catabolites.

Lingua originale	English
pagine (da-a)	165-196
Numero di pagine	32
Rivista	Critical Reviews in Biochemistry and Molecular Biology
Volume	30
DOI	https://doi.org/10.3109/10409239509085142
Stato di pubblicazione	Pubblicato - 1995

Keywords

HEMOGLOBIN

OSS delle Nazioni Unite

Questo processo contribuisce al raggiungimento dei seguenti obiettivi di sviluppo sostenibile

Accesso al documento

10.3109/10409239509085142

Altri file e collegamenti

Link a IRIS PubliCatt

Cita questo

@article{2617632addb34e6b9bf1d9869c66fe19,

title = "THE MULTIPLE FUNCTIONS OF HEMOGLOBIN",

abstract = "The aim of this review is to focus and discuss several parallel biological functions of hemoglobin besides its basic function of oxygen transport. In light of the information present in the literature the following possible physiological roles of hemoglobin are discussed: (1) hemoglobin as molecular heat transducer through its oxygenation-deoxygenation cycle, (2) hemoglobin as modulator of erythrocyte metabolism, (3) hemoglobin oxidation as an onset of erythrocyte senescence, (4) hemoglobin and its implication in genetic resistance to malaria, (5) enzymatic activities of hemoglobin and interactions with drugs, and (6) hemoglobin as source of physiological active catabolites.",

keywords = "HEMOGLOBIN, HEMOGLOBIN",

author = "Bruno Giardina and I Messana and Roberto Scatena and Massimo Castagnola",

year = "1995",

doi = "10.3109/10409239509085142",

language = "English",

volume = "30",

pages = "165--196",

journal = "Critical Reviews in Biochemistry and Molecular Biology",

issn = "1040-9238",

publisher = "CRC Press LLC:2000 Northwest Corporate Boulevard:Boca Raton, FL 33431:(800)272-7737, (561)994-0555, EMAIL: [email protected], [email protected], INTERNET: http://www.crcpress.com, Fax: (561)361-6076",

}

TY - JOUR

T1 - THE MULTIPLE FUNCTIONS OF HEMOGLOBIN

AU - Giardina, Bruno

AU - Messana, I

AU - Scatena, Roberto

AU - Castagnola, Massimo

PY - 1995

Y1 - 1995

N2 - The aim of this review is to focus and discuss several parallel biological functions of hemoglobin besides its basic function of oxygen transport. In light of the information present in the literature the following possible physiological roles of hemoglobin are discussed: (1) hemoglobin as molecular heat transducer through its oxygenation-deoxygenation cycle, (2) hemoglobin as modulator of erythrocyte metabolism, (3) hemoglobin oxidation as an onset of erythrocyte senescence, (4) hemoglobin and its implication in genetic resistance to malaria, (5) enzymatic activities of hemoglobin and interactions with drugs, and (6) hemoglobin as source of physiological active catabolites.

AB - The aim of this review is to focus and discuss several parallel biological functions of hemoglobin besides its basic function of oxygen transport. In light of the information present in the literature the following possible physiological roles of hemoglobin are discussed: (1) hemoglobin as molecular heat transducer through its oxygenation-deoxygenation cycle, (2) hemoglobin as modulator of erythrocyte metabolism, (3) hemoglobin oxidation as an onset of erythrocyte senescence, (4) hemoglobin and its implication in genetic resistance to malaria, (5) enzymatic activities of hemoglobin and interactions with drugs, and (6) hemoglobin as source of physiological active catabolites.

KW - HEMOGLOBIN

UR - http://hdl.handle.net/10807/23749

U2 - 10.3109/10409239509085142

DO - 10.3109/10409239509085142

M3 - Article

SN - 1040-9238

VL - 30

SP - 165

EP - 196

JO - Critical Reviews in Biochemistry and Molecular Biology

JF - Critical Reviews in Biochemistry and Molecular Biology

ER -

THE MULTIPLE FUNCTIONS OF HEMOGLOBIN

Abstract

Keywords

OSS delle Nazioni Unite

Accesso al documento

Altri file e collegamenti

Fingerprint

Cita questo