Abstract
Axonal injury causes devastating neural impairment, which is often permanent after central nervous system (CNS) damage. Axon regeneration failure is largely responsible for these long-term deficits and poor functional recovery, and is attributable to cell-intrinsic mechanisms and to the nonpermissive cell-extrinsic environment, which together limit axon regrowth.
Lingua originale | English |
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Titolo della pubblicazione ospite | Epigenetics and Regeneration |
Pagine | 333-354 |
Numero di pagine | 22 |
Volume | 11 |
DOI | |
Stato di pubblicazione | Pubblicato - 2019 |
Keywords
- Axonal regeneration
- Dorsal root ganglia
- Epigenetics
- Optic nerve injury
- Regeneration-associated genes (RAGs)
- Spinal cord injury