Abstract

Axonal injury causes devastating neural impairment, which is often permanent after central nervous system (CNS) damage. Axon regeneration failure is largely responsible for these long-term deficits and poor functional recovery, and is attributable to cell-intrinsic mechanisms and to the nonpermissive cell-extrinsic environment, which together limit axon regrowth.
Lingua originaleEnglish
Titolo della pubblicazione ospiteEpigenetics and Regeneration
Pagine333-354
Numero di pagine22
Volume11
DOI
Stato di pubblicazionePubblicato - 2019

Keywords

  • Axonal regeneration
  • Dorsal root ganglia
  • Spinal cord injury
  • Optic nerve injury
  • Regeneration-associated genes (RAGs)
  • Epigenetics

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