The impact of preoperative ASA-physical status on postoperative complications and long-term survival outcomes in gastric cancer patients

Fausto Rosa, Giuseppe Quero, Liliana Sollazzi, Sergio Alfieri, Antonio Pio Tortorelli, Claudio Fiorillo

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

Abstract

OBJECTIVE: The aim of this study was to investigate the impact of the preoperative American Society of Anesthesiologists-Physical status (ASA-PS) on both the short-term and long-term outcomes in patients with Gastric Cancer (GC). PATIENTS AND METHODS: In a retrospective observational study, a total of 473 GC patients were divided into the following 3 groups: ASA 1, ASA 2, and ASA 3-4. RESULTS: The ASA 3-4 group included significantly older patients compared to the other groups (p<0.0001). In ASA 1 patients, there was a higher number of lymph nodes dissected (p=0.006), and more patients received adjuvant treatment (p<0.001). In the three groups, no difference regarding the postoperative surgical and medical complications (p=0.29 and p=0.1, respectively) nor in terms of mortality rate (p=0.17) were demonstrated. The multivariate analysis showed that age, tumor stage, number of lymph nodes dissected, positive lymph nodes, adjuvant treatments, and postoperative surgical complications were significant predictive factors for mortality. Five-year overall and disease-free survival for ASA 1, ASA 2, and ASA 3-4 groups was 56%, 57.6%, and 44%, respectively; and 37%, 44.3%, and 39.2%, respectively. CONCLUSIONS: Preoperative ASA-PS alone cannot serve as a direct operative risk indicator for GC patients.
Lingua originaleEnglish
pagine (da-a)7383-7390
Numero di pagine8
RivistaEuropean Review for Medical and Pharmacological Sciences
Volume23
DOI
Stato di pubblicazionePubblicato - 2019

Keywords

  • ASA-Physical status
  • Gastric cancer
  • Morbidity
  • Mortality

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