The immunocytochemical expression of VE-1 (BRAF V600E-related) antibody identifies the aggressive variants of papillary thyroid carcinoma on liquid-based cytology

Maurizio Martini, Alfredo Pontecorvi, Patrizia Straccia, Chiara Brunelli, Teresa Musarra, Celestino Pio Lombardi, Guido Fadda, Esther D Rossi, Paola Lanza

Risultato della ricerca: Contributo in rivistaArticolo in rivista

4 Citazioni (Scopus)

Abstract

The recently introduced monoclonal V600E antibody (clone VE1) is likely to be an alternative strategy for detecting this mutation in thyroid lesions. Although VE1 immunostaining and molecular methods used to assess papillary thyroid carcinoma in surgical specimens are in good agreement, evaluation of VE1 in cytology and cell block samples is rarely performed, and its diagnostic value in cytology has not been well established. In this study, we sought to determine if VE1 is suitable for FNA and cell block method.
Lingua originaleEnglish
pagine (da-a)1-23
Numero di pagine23
RivistaCytopathology
DOI
Stato di pubblicazionePubblicato - 2019

Keywords

  • BRAFV600E antibody (clone VE1)
  • PTC
  • Thyroid nodules
  • cell block
  • fine needle aspiration

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