The heparin management test: a new device for monitoring anticoagulation during coronary intervention

G Helft; Paolo Bartolomeo; Ag Zaman; Sg Worthley; S Chokron; C Le Pailleur; F Beygui; C Le Feuvre; Jp Metzger; A Vacheron; Mm Samama

The heparin management test: a new device for monitoring anticoagulation during coronary intervention

G Helft, Paolo Bartolomeo, Ag Zaman, Sg Worthley, S Chokron, C Le Pailleur, F Beygui, C Le Feuvre, Jp Metzger, A Vacheron, Mm Samama

Risultato della ricerca: Contributo in rivista › Articolo in rivista

5 Citazioni (Scopus)

Abstract

Whole blood coagulation analysers are widely used during percutaneous coronary interventions. The precise degree of anticoagulation in patients is important in this setting. The aim of this investigation was to compare the results obtained with ACT (Hemochron) and HMT, the Heparin Management Test (TAS) in patients undergoing percutaneous coronary interventions. Patients (n = 100) were enrolled prospectively. Each patient received 10,000 units of heparin. At the end of the procedure, the mean ACT was 284+/-31 seconds and the mean HMT was 292+/-33 seconds. The correlation between the two methods was highly significant (r = 0.64, p<0.001). The HMT correlates well with ACT values in patients undergoing percutaneous coronary interventions. Its use in the management of these patients should be considered.

Lingua originale	English
pagine (da-a)	481-485
Numero di pagine	5
Rivista	Thrombosis Research
Volume	96
Stato di pubblicazione	Pubblicato - 1999
Pubblicato esternamente	Sì

Keywords

Angina, Unstable
Angioplasty, Balloon, Coronary
Anticoagulants
Blood Coagulation
Blood Coagulation Tests
Drug Monitoring
Evaluation Studies as Topic
Female
Heparin
Humans
Injections, Intravenous
Linear Models
Male
Middle Aged
Prospective Studies
Reproducibility of Results
Whole Blood Coagulation Time

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title = "The heparin management test: a new device for monitoring anticoagulation during coronary intervention",

abstract = "Whole blood coagulation analysers are widely used during percutaneous coronary interventions. The precise degree of anticoagulation in patients is important in this setting. The aim of this investigation was to compare the results obtained with ACT (Hemochron) and HMT, the Heparin Management Test (TAS) in patients undergoing percutaneous coronary interventions. Patients (n = 100) were enrolled prospectively. Each patient received 10,000 units of heparin. At the end of the procedure, the mean ACT was 284+/-31 seconds and the mean HMT was 292+/-33 seconds. The correlation between the two methods was highly significant (r = 0.64, p<0.001). The HMT correlates well with ACT values in patients undergoing percutaneous coronary interventions. Its use in the management of these patients should be considered.",

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author = "G Helft and Paolo Bartolomeo and Ag Zaman and Sg Worthley and S Chokron and {Le Pailleur}, C and F Beygui and {Le Feuvre}, C and Jp Metzger and A Vacheron and Mm Samama",

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language = "English",

volume = "96",

pages = "481--485",

journal = "Thrombosis Research",

issn = "0049-3848",

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TY - JOUR

T1 - The heparin management test: a new device for monitoring anticoagulation during coronary intervention

AU - Helft, G

AU - Bartolomeo, Paolo

AU - Zaman, Ag

AU - Worthley, Sg

AU - Chokron, S

AU - Le Pailleur, C

AU - Beygui, F

AU - Le Feuvre, C

AU - Metzger, Jp

AU - Vacheron, A

AU - Samama, Mm

PY - 1999

Y1 - 1999

N2 - Whole blood coagulation analysers are widely used during percutaneous coronary interventions. The precise degree of anticoagulation in patients is important in this setting. The aim of this investigation was to compare the results obtained with ACT (Hemochron) and HMT, the Heparin Management Test (TAS) in patients undergoing percutaneous coronary interventions. Patients (n = 100) were enrolled prospectively. Each patient received 10,000 units of heparin. At the end of the procedure, the mean ACT was 284+/-31 seconds and the mean HMT was 292+/-33 seconds. The correlation between the two methods was highly significant (r = 0.64, p<0.001). The HMT correlates well with ACT values in patients undergoing percutaneous coronary interventions. Its use in the management of these patients should be considered.

AB - Whole blood coagulation analysers are widely used during percutaneous coronary interventions. The precise degree of anticoagulation in patients is important in this setting. The aim of this investigation was to compare the results obtained with ACT (Hemochron) and HMT, the Heparin Management Test (TAS) in patients undergoing percutaneous coronary interventions. Patients (n = 100) were enrolled prospectively. Each patient received 10,000 units of heparin. At the end of the procedure, the mean ACT was 284+/-31 seconds and the mean HMT was 292+/-33 seconds. The correlation between the two methods was highly significant (r = 0.64, p<0.001). The HMT correlates well with ACT values in patients undergoing percutaneous coronary interventions. Its use in the management of these patients should be considered.

KW - Angina, Unstable

KW - Angioplasty, Balloon, Coronary

KW - Anticoagulants

KW - Blood Coagulation

KW - Blood Coagulation Tests

KW - Drug Monitoring

KW - Evaluation Studies as Topic

KW - Female

KW - Heparin

KW - Humans

KW - Injections, Intravenous

KW - Linear Models

KW - Male

KW - Middle Aged

KW - Prospective Studies

KW - Reproducibility of Results

KW - Whole Blood Coagulation Time

KW - Angina, Unstable

KW - Angioplasty, Balloon, Coronary

KW - Anticoagulants

KW - Blood Coagulation

KW - Blood Coagulation Tests

KW - Drug Monitoring

KW - Evaluation Studies as Topic

KW - Female

KW - Heparin

KW - Humans

KW - Injections, Intravenous

KW - Linear Models

KW - Male

KW - Middle Aged

KW - Prospective Studies

KW - Reproducibility of Results

KW - Whole Blood Coagulation Time

UR - http://hdl.handle.net/10807/21103

M3 - Article

SN - 0049-3848

VL - 96

SP - 481

EP - 485

JO - Thrombosis Research

JF - Thrombosis Research

ER -

The heparin management test: a new device for monitoring anticoagulation during coronary intervention

Abstract

Keywords

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