Background: Glycated hemoglobin (HbA1c) is widely used as a clinical marker of long-term blood glucose concentration in patients with diabetes. The clinical laboratory plays a vital role in the diagnosis and management of diabetes. Many methods for the measurement of HbA1c have been developed based on different analytical principles, often causing discordant results. For this reason, the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) established a reference method for HbA1c assay, namely, high-performance liquid chromatography-mass spectrometry/capillary electrophoresis (HPLC-MS/CE).
- glycated hemoglobin