The hbhA gene of Mycobacterium tuberculosis is specifically upregulated in the lungs but not in the spleens of aerogenically infected mice

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28 Citazioni (Scopus)

Abstract

We report that hbhA is differentially regulated during Mycobacterium tuberculosis infection. Upregulation was observed in epithelial cell infection but not in macrophage infection and in the lungs but not in the spleens of infected mice, and it was greater during the early steps of infection, when bacilli disseminate from the site of primary infection.
Lingua originaleEnglish
pagine (da-a)3006-3011
Numero di pagine6
RivistaInfection and Immunity
Volume74
DOI
Stato di pubblicazionePubblicato - 2006

Keywords

  • Animals
  • Bacterial Proteins
  • Cytoskeletal Proteins
  • Female
  • Gene Expression Regulation, Bacterial
  • Lung
  • Membrane Proteins
  • Mice
  • Mice, Inbred C57BL
  • Organ Specificity
  • Recombinant Proteins
  • Spleen
  • Up-Regulation

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