The harmonic study: cost-effectiveness evaluation of the use of the ultrasonic scalpel in total thyroidectomy

Matteo Ruggeri, Rossella Dibidino, Marco Marchetti, Celestino Pio Lombardi, Marco Raffaelli, Americo Cicchetti

Risultato della ricerca: Contributo in rivistaArticolo in rivista

13 Citazioni (Scopus)


BACKGROUND: Total thyroidectomy (TT) can be performed either with the traditional technique or using the ultrasound scalpel. Here, the use of the ultrasound scalpel is investigated in order to assess cost-effectiveness from an hospital, third party payer and societal perspective. METHODS: A randomized controlled trial was conducted at the University Hospital A. Gemelli in Rome. Data refer to 198 patients, randomized to either surgery with the ultrasound scalpel (n = 96) or traditional (n = 102) and followed for 3 months after hospital discharge. Operation time (OT) and resource consumption were recorded. Main clinical outcome investigated was quality of life (evaluated with EQ-5D). RESULTS: A shorter operation time (traditional: 76.36 vs ultrasound: 54.16 minutes, p < 0.001) was observed. 3 months after surgery, differences in QoL were significant (0.91 vs 0.84, p = 0.002). Concerning the hospital perspective, ultrasound scalpel allows savings of 119 EUR per patient. From a societal perspective, ultrasound scalpel is also related to lower medical resource consumption during a 3 month follow-up after discharge (traditional: 129.03 EUR vs ultrasound: 107.82 EUR) and lower non-medical resource utilization (transport/hotels costs traditional:535.51 EUR vs ultrasound: 342.77 EUR. No statistical difference was found in productivity losses up to 3 months (traditional: 377.71 EUR vs ultrasound: 385.51 EUR). CONCLUSION: Allowing an overall saving of 325.36 EUR per patient, Ultrasound scalpel should be adopted for TT procedures in the "A.Gemelli" University hospital
Lingua originaleEnglish
pagine (da-a)259-264
Numero di pagine6
RivistaInternational Journal of Technology Assessment in Health Care
Stato di pubblicazionePubblicato - 2012


  • Adult
  • Aged
  • Cost-Benefit Analysis
  • Female
  • Humans
  • Male
  • Middle Aged
  • Rome
  • Surgical Instruments
  • Thyroidectomy
  • Ultrasonic Therapy
  • Young Adult


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