The effect of multifactorial lifestyle interventions on cardiovascular risk factors: a systematic review and meta-analysis of trials conducted in the general population and high risk groups

Walter Ricciardi, Leuconoe Grazia Sisti, E. Shkurti

Risultato della ricerca: Contributo in rivistaArticolo in rivista

28 Citazioni (Scopus)

Abstract

Cardiovascular diseases (CVDs) are the leading cause of premature mortality and disability accounting for one third of all deaths worldwide with considerable impacts on economics and on the quality of life. The evidence suggests that a multifactorial lifestyle intervention might have a role in the CVDs risk reduction, especially in the risk populations, nonetheless the effects on modifiable CVDs risk factors have not been completely explored. Our work aimed at evaluating the impact of multifactorial lifestyle interventions on cardiovascular risk modification, both in the general and risk population. A systematic review and meta-analysis of the randomized controlled trials (RCTs) were performed by including articles published up to April 16th, 2016. RCTs were selected if they had investigated the impact of multifactorial lifestyle interventions on lipids, blood pressure, BMI and waist circumference, smoking and physical activity. Changes in the level of modifiable risk factors from baseline were evaluated. Search resulted in 19,847 studies, of which 36 were included in the analysis. Compared to a usual care, the multifactorial lifestyle intervention is able to lower the blood pressure, total cholesterol, BMI and waist circumference, at both 6 and 12 months, and to increase physical activity at 12 months. Better results were obtained in primary prevention and in moderate and high risk groups. Multifactorial lifestyle interventions clearly represent a valid tool for reducing the cardiovascular risk factors and should be implemented in the risk groups and in primary prevention.
Lingua originaleEnglish
pagine (da-a)82-97
Numero di pagine16
RivistaPreventive Medicine
Volume109
DOI
Stato di pubblicazionePubblicato - 2018

Keywords

  • Blood Pressure
  • Body Mass Index
  • Cardiovascular Diseases
  • Cardiovascular diseases
  • Cardiovascular prevention
  • Cardiovascular risk factors
  • Epidemiology
  • Exercise
  • Humans
  • Life Style
  • Lifestyle
  • Meta-analysis
  • Public Health, Environmental and Occupational Health
  • Randomized Controlled Trials as Topic
  • Risk Factors
  • Risk Reduction Behavior
  • Systematic review

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