The detection of neural autoantibodies in patients with antiepileptic-drug-resistant epilepsy predicts response to immunotherapy

Giacomo Della Marca; Amelia Evoli; Paolo Maria Rossini; G. Assenza; M. Tombini; A. Benvenga

doi:10.1111/ene.12529

The detection of neural autoantibodies in patients with antiepileptic-drug-resistant epilepsy predicts response to immunotherapy

Giacomo Della Marca, Amelia Evoli, Paolo Maria Rossini, G. Assenza, M. Tombini, A. Benvenga

Risultato della ricerca: Contributo in rivista › Articolo in rivista

23 Citazioni (Scopus)

Abstract

The detection of antibodies binding neural antigens in patients with epilepsy has led to the definition of 'autoimmune epilepsy'. Patients with neural antibodies not responding to antiepileptic drugs (AEDs) may benefit from immunotherapy. Aim of this study was to evaluate the frequency of autoantibodies specific to neural antigens in patients with epilepsy and their response to immunotherapy.

Lingua originale	English
pagine (da-a)	70-78
Numero di pagine	9
Rivista	EUROPEAN JOURNAL OF NEUROLOGY
Volume	22
DOI	https://doi.org/10.1111/ene.12529
Stato di pubblicazione	Pubblicato - 2014

Keywords

antiepileptic drug resistant epilepsy
autoimmune epilepsy
leucine-rich glioma inactivated 1
synaptic antigens

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10.1111/ene.12529

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abstract = "The detection of antibodies binding neural antigens in patients with epilepsy has led to the definition of 'autoimmune epilepsy'. Patients with neural antibodies not responding to antiepileptic drugs (AEDs) may benefit from immunotherapy. Aim of this study was to evaluate the frequency of autoantibodies specific to neural antigens in patients with epilepsy and their response to immunotherapy.",

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AU - Della Marca, Giacomo

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AU - Rossini, Paolo Maria

AU - Assenza, G.

AU - Tombini, M.

AU - Benvenga, A.

PY - 2014

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N2 - The detection of antibodies binding neural antigens in patients with epilepsy has led to the definition of 'autoimmune epilepsy'. Patients with neural antibodies not responding to antiepileptic drugs (AEDs) may benefit from immunotherapy. Aim of this study was to evaluate the frequency of autoantibodies specific to neural antigens in patients with epilepsy and their response to immunotherapy.

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KW - antiepileptic drug resistant epilepsy

KW - autoimmune epilepsy

KW - leucine-rich glioma inactivated 1

KW - synaptic antigens

KW - antiepileptic drug resistant epilepsy

KW - autoimmune epilepsy

KW - leucine-rich glioma inactivated 1

KW - synaptic antigens

UR - http://hdl.handle.net/10807/62326

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DO - 10.1111/ene.12529

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The detection of neural autoantibodies in patients with antiepileptic-drug-resistant epilepsy predicts response to immunotherapy

Abstract

Keywords

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