The decrease of serum levels of human neutrophil alpha-defensins parallels with the surgery-induced amelioration of NASH in obesity

Melania Manco; José Manuel Fernandez-Real; Fabio Maria Vecchio; Valerio Gaetano Vellone; José María Moreno; Vincenzo Tondolo; Gianfranco Bottazzo; Giuseppe Nanni; Geltrude Mingrone

doi:10.1007/s11695-010-0129-8

The decrease of serum levels of human neutrophil alpha-defensins parallels with the surgery-induced amelioration of NASH in obesity

Melania Manco
, José Manuel Fernandez-Real
, Fabio Maria Vecchio
, Valerio Gaetano Vellone
, José María Moreno
, Vincenzo Tondolo
, Gianfranco Bottazzo
, Giuseppe Nanni
, Geltrude Mingrone

University of Girona
IRCCS Ospedale pediatrico Bambino Gesù - Roma

Risultato della ricerca: Contributo in rivista › Articolo

13 Citazioni (Scopus)

Abstract

Innate immune system participates actively into inflammatory processes, with immune cells and liver secreting a number of immune peptides. Among them, both soluble CD14 receptor (sCD14) and human neutrophil alpha-defensins (HNDs) may represent serum markers of necro-inflammation in obese patients with non-alcoholic fatty liver disease.

Lingua originale	Inglese
pagine (da-a)	1682-1689
Numero di pagine	8
Rivista	Obesity Surgery
Volume	20
DOI	https://doi.org/10.1007/s11695-010-0129-8
Stato di pubblicazione	Pubblicato - 2010

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Keywords

Adult
Antigens, CD14
Biliopancreatic Diversion
Biological Markers
Body Mass Index
Fatty Liver
Female
Humans
Inflammation
Insulin Resistance
Obesity, Morbid
Weight Loss
Young Adult
alpha-Defensins

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10.1007/s11695-010-0129-8

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title = "The decrease of serum levels of human neutrophil alpha-defensins parallels with the surgery-induced amelioration of NASH in obesity",

abstract = "Innate immune system participates actively into inflammatory processes, with immune cells and liver secreting a number of immune peptides. Among them, both soluble CD14 receptor (sCD14) and human neutrophil alpha-defensins (HNDs) may represent serum markers of necro-inflammation in obese patients with non-alcoholic fatty liver disease.",

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author = "Melania Manco and Fernandez-Real, \{Jos{\'e} Manuel\} and Vecchio, \{Fabio Maria\} and Vellone, \{Valerio Gaetano\} and Moreno, \{Jos{\'e} Mar{\'i}a\} and Vincenzo Tondolo and Gianfranco Bottazzo and Giuseppe Nanni and Geltrude Mingrone",

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doi = "10.1007/s11695-010-0129-8",

language = "English",

volume = "20",

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journal = "Obesity Surgery",

issn = "0960-8923",

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T1 - The decrease of serum levels of human neutrophil alpha-defensins parallels with the surgery-induced amelioration of NASH in obesity

AU - Manco, Melania

AU - Fernandez-Real, José Manuel

AU - Vecchio, Fabio Maria

AU - Vellone, Valerio Gaetano

AU - Moreno, José María

AU - Tondolo, Vincenzo

AU - Bottazzo, Gianfranco

AU - Nanni, Giuseppe

AU - Mingrone, Geltrude

PY - 2010

Y1 - 2010

N2 - Innate immune system participates actively into inflammatory processes, with immune cells and liver secreting a number of immune peptides. Among them, both soluble CD14 receptor (sCD14) and human neutrophil alpha-defensins (HNDs) may represent serum markers of necro-inflammation in obese patients with non-alcoholic fatty liver disease.

AB - Innate immune system participates actively into inflammatory processes, with immune cells and liver secreting a number of immune peptides. Among them, both soluble CD14 receptor (sCD14) and human neutrophil alpha-defensins (HNDs) may represent serum markers of necro-inflammation in obese patients with non-alcoholic fatty liver disease.

KW - Adult

KW - Antigens, CD14

KW - Biliopancreatic Diversion

KW - Biological Markers

KW - Body Mass Index

KW - Fatty Liver

KW - Female

KW - Humans

KW - Inflammation

KW - Insulin Resistance

KW - Obesity, Morbid

KW - Weight Loss

KW - Young Adult

KW - alpha-Defensins

KW - Adult

KW - Antigens, CD14

KW - Biliopancreatic Diversion

KW - Biological Markers

KW - Body Mass Index

KW - Fatty Liver

KW - Female

KW - Humans

KW - Inflammation

KW - Insulin Resistance

KW - Obesity, Morbid

KW - Weight Loss

KW - Young Adult

KW - alpha-Defensins

UR - http://hdl.handle.net/10807/7194

U2 - 10.1007/s11695-010-0129-8

DO - 10.1007/s11695-010-0129-8

M3 - Article

SN - 0960-8923

VL - 20

SP - 1682

EP - 1689

JO - Obesity Surgery

JF - Obesity Surgery

ER -

The decrease of serum levels of human neutrophil alpha-defensins parallels with the surgery-induced amelioration of NASH in obesity

Abstract

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Keywords

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