The decrease of serum levels of human neutrophil alpha-defensins parallels with the surgery-induced amelioration of NASH in obesity

Geltrude Mingrone, Melania Manco, Valerio Gaetano Vellone, Vincenzo Tondolo, Giuseppe Nanni, José Manuel Fernandez-Real, José María Moreno, Gianfranco Bottazzo

Risultato della ricerca: Contributo in rivistaArticolo in rivista

13 Citazioni (Scopus)

Abstract

Innate immune system participates actively into inflammatory processes, with immune cells and liver secreting a number of immune peptides. Among them, both soluble CD14 receptor (sCD14) and human neutrophil alpha-defensins (HNDs) may represent serum markers of necro-inflammation in obese patients with non-alcoholic fatty liver disease.
Lingua originaleEnglish
pagine (da-a)1682-1689
Numero di pagine8
RivistaObesity Surgery
Volume20
DOI
Stato di pubblicazionePubblicato - 2010

Keywords

  • Adult
  • Antigens, CD14
  • Biliopancreatic Diversion
  • Biological Markers
  • Body Mass Index
  • Fatty Liver
  • Female
  • Humans
  • Inflammation
  • Insulin Resistance
  • Obesity, Morbid
  • Weight Loss
  • Young Adult
  • alpha-Defensins

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