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The burden of mental disorders, substance use disorders and self-harm among young people in Europe, 1990–2019: Findings from the Global Burden of Disease Study 2019

  • Giulio Castelpietra*
  • , Ann Kristin Skrindo Knudsen
  • , Emilie E. Agardh
  • , Benedetta Armocida
  • , Massimiliano Beghi
  • , Kim Moesgaard Iburg
  • , Giancarlo Logroscino
  • , Rui Ma
  • , Fabrizio Starace
  • , Nicholas Steel
  • , Giovanni Addolorato
  • , Catalina Liliana Andrei
  • , Tudorel Andrei
  • , Jose L Ayuso-Mateos
  • , Maciej Banach
  • , Till Winfried Bärnighausen
  • , Francesco Barone-Adesi
  • , Akshaya Srikanth Bhagavathula
  • , Felix Carvalho
  • , Márcia Carvalho
  • Joht Singh Chandan, Vijay Kumar Chattu, Rosa A. S. Couto, Natália Cruz-Martins, Paul I. Dargan, Keshab Deuba, Diana Dias da Silva, Adeniyi Francis Fagbamigbe, Eduarda Fernandes, Pietro Ferrara, Florian Fischer, Peter Andras Gaal, Alessandro Gialluisi, Juanita A. Haagsma, Josep Maria Haro, M. Tasdik Hasan, Syed Shahzad Hasan, Sorin Hostiuc, Licia Iacoviello, Ivo Iavicoli, Elham Jamshidi, Jost B. Jonas, Tamas Joo, Jacek Jerzy Jozwiak, Srinivasa Vittal Katikireddi, Joonas H. Kauppila, Moien A. B. Khan, Adnan Kisa, Sezer Kisa, Mika Kivimäki, Kamrun Nahar Koly, Ai Koyanagi, Manasi Kumar, Tea Lallukka, Berthold Langguth, Caterina Ledda, Paul H. Lee, Ilaria Lega, Christine Linehan, Joana A. Loureiro, Áurea M Madureira-Carvalho, Jose Martinez-Raga, Manu Raj Mathur, John J. McGrath, Enkeleint A. Mechili, Alexios-Fotios A. Mentis, Tomislav Mestrovic, Bartosz Miazgowski, Andreea Mirica, Antonio Mirijello, Babak Moazen, Shafiu Mohammed, Francesk Mulita, Gabriele Nagel, Ionut Negoi, Ruxandra Irina Negoi, Vincent Ebuka Nwatah, Alicia Padron-Monedero, Songhomitra Panda-Jonas, Shahina Pardhan, Maja Pasovic, Jay Patel, Ionela-Roxana Petcu, Marina Pinheiro, Richard Charles G. Pollok, Maarten J. Postma, David Laith Rawaf, Salman Rawaf, Esperanza Romero-Rodríguez, Luca Ronfani, Dominic Sagoe, Francesco Sanmarchi, Michael P Schaub, Nigussie Tadesse Sharew, Rahman Shiri, Farhad Shokraneh, Inga Dora Sigfusdottir, João Pedro Silva, Renata Silva, Bogdan Socea, Miklós Szócska, Rafael Tabarés-Seisdedos, Marco Torrado, Marcos Roberto Tovani-Palone, Tommi Juhani Vasankari, Massimiliano Veroux, Russell M. Viner, Andrea Werdecker, Andrea Sylvia Winkler, Simon I. Hay, Alize J. Ferrari, Mohsen Naghavi, Peter Allebeck, Lorenzo Monasta
*Autore corrispondente per questo lavoro
  • Region Friuli Venezia Giulia
  • Norwegian Institute of Public Health
  • Karolinska Institutet
  • Istituto Superiore di Sanita
  • AUSL Diabetes Unit Romagna
  • Aarhus University
  • University of Bari
  • University of Washington
  • Azienda USL di Modena
  • University of East Anglia
  • UK Health Security Agency
  • Carol Davila University of Medicine and Pharmacy
  • Medical University of Łódź
  • Institute of Polish Mother's Health Center
  • Harvard University
  • Heidelberg University 
  • University of Eastern Piedmont
  • United Arab Emirates University
  • Charles University
  • University of Porto
  • University Fernando Pessoa
  • University of Birmingham
  • The University of the West Indies
  • Guy’s & St Thomas’ NHS FT
  • Faculty of Life Sciences & Medicine
  • University of St Andrews
  • University of Ibadan
  • University of Milan - Bicocca
  • Charité – Universitätsmedizin Berlin
  • Sapientia Hungarian University of Transylvania
  • Semmelweis University
  • IRCCS Istituto Neurologico Mediterraneo Neuromed - Pozzilli (IS)
  • Erasmus Medical Center
  • CIBER - Center for Biomedical Research Network
  • University of Barcelona
  • University of Huddersfield
  • University of Newcastle
  • University of Liverpool
  • University of Insubria
  • University of Lausanne
  • Shahid Beheshti University of Medical Sciences
  • Institute of Molecular and Clinical Ophthalmology Basel
  • University of Opole
  • University of Glasgow
  • University of Oulu
  • Kristiania University College
  • Tulane University
  • Oslo Metropolitan University
  • University of Helsinki
  • University College London
  • International Centre for Diarrhoeal Disease Research Bangladesh
  • ICREA
  • University of Nairobi
  • University of Regensburg
  • University of Catania
  • University of Leicester
  • University College Dublin
  • Polytechnic Institute of Porto
  • University of Valencia
  • Hospital Universitario Dr. Peset
  • Public Health Foundation of India
  • University of Queensland
  • University of Vlora
  • University of Crete
  • University North
  • Dr. Zora Profozic Polyclinic
  • Pomeranian Medical University in Szczecin
  • Bucharest University of Economic Studies
  • IRCCS Ospedale Casa Sollievo della Sofferenza - San Giovanni Rotondo (FG)
  • Frankfurt University of Applied Sciences
  • Technical University of Berlin
  • Ahmadu Bello University
  • University of Patras
  • University of Thessaly
  • Ulm University
  • Emergency Hospital of Bucharest
  • National Hospital Abuja
  • Escuela Nacional de Sanidad
  • Privatpraxis
  • Anglia Ruskin University
  • University of Leeds
  • University of Edinburgh
  • St. George's University of London
  • University of Groningen
  • Imperial College London
  • University College London Hospital
  • Maimonides Biomedical Research Institute of Cordoba (IMIBIC)
  • IRCCS Ospedale Infantile Burlo Garofolo - Trieste
  • University of Bergen
  • University of Bologna
  • Debre Berhan University
  • Finnish Institute of Occupational Health
  • King's College London
  • University of Nottingham
  • Columbia University
  • Reykjavík University
  • "Sf. Pantelimon" Emergency Clinical Hospital Bucharest

Risultato della ricerca: Contributo in rivistaArticolo

Abstract

Background: Mental health is a public health issue for European young people, with great heterogeneity in resource allocation. Representative population-based studies are needed. The Global Burden of Disease (GBD) Study 2019 provides internationally comparable information on trends in the health status of populations and changes in the leading causes of disease burden over time. Methods: Prevalence, incidence, Years Lived with Disability (YLDs) and Years of Life Lost (YLLs) from mental disorders (MDs), substance use disorders (SUDs) and self-harm were estimated for young people aged 10-24 years in 31 European countries. Rates per 100,000 population, percentage changes in 1990-2019, 95% Uncertainty Intervals (UIs), and correlations with Sociodemographic Index (SDI), were estimated. Findings: In 2019, rates per 100,000 population were 16,983 (95% UI 12,823 – 21,630) for MDs, 3,891 (3,020 - 4,905) for SUDs, and 89·1 (63·8 - 123·1) for self-harm. In terms of disability, anxiety contributed to 647·3 (432–912·3) YLDs, while in terms of premature death, self-harm contributed to 319·6 (248·9–412·8) YLLs, per 100,000 population. Over the 30 years studied, YLDs increased in eating disorders (14·9%;9·4-20·1) and drug use disorders (16·9%;8·9-26·3), and decreased in idiopathic developmental intellectual disability (–29·1%;23·8-38·5). YLLs decreased in self-harm (–27·9%;38·3-18·7). Variations were found by sex, age-group and country. The burden of SUDs and self-harm was higher in countries with lower SDI, MDs were associated with SUDs. Interpretation: Mental health conditions represent an important burden among young people living in Europe. National policies should strengthen mental health, with a specific focus on young people. Funding: The Bill and Melinda Gates Foundation
Lingua originaleInglese
pagine (da-a)N/A-N/A
RivistaThe Lancet Regional Health - Europe
Volume16
Numero di pubblicazionen/a
DOI
Stato di pubblicazionePubblicato - 2022

OSS delle Nazioni Unite

Questo processo contribuisce al raggiungimento dei seguenti obiettivi di sviluppo sostenibile

  1. SDG 3 - Salute e benessere
    SDG 3 Salute e benessere

All Science Journal Classification (ASJC) codes

  • Medicina Interna
  • Oncologia
  • Politiche della Salute

Keywords

  • Europe
  • Mental disorders
  • Mental health
  • Self-harm
  • Substance use
  • Young people

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