The association between coronary graft patency and clinical status in patients with coronary artery disease

Mario Fulvio Luigi Gaudino, Antonino Di Franco, Deepak L Bhatt, John H Alexander, Antonio Abbate, Lorenzo Azzalini, Sigrid Sandner, Garima Sharma, Sunil V Rao, Filippo Crea, Stephen E Fremes, Sripal Bangalore

Risultato della ricerca: Contributo in rivistaArticolo in rivista

Abstract

The concept of a direct association between coronary graft patency and clinical status is generally accepted. However, the relationship is more complex and variable than usually thought. Key issues are the lack of a common definition of graft occlusion and of a standardized imaging protocol for patients undergoing coronary bypass surgery. Factors like the type of graft, the timing of the occlusion, and the amount of myocardium at risk, as well as baseline patients' characteristics, modulate the patency-to-clinical status association. Available evidence suggests that graft occlusion is more often associated with non-fatal events rather than death. Also, graft failure due to competitive flow is generally a benign event, while graft occlusion in a graft-dependent circulation is associated with clinical symptoms. In this systematic review, we summarize the evidence on the association between graft status and clinical outcomes.
Lingua originaleEnglish
pagine (da-a)1433-1441
Numero di pagine9
RivistaEuropean Heart Journal
Volume42
DOI
Stato di pubblicazionePubblicato - 2021

Keywords

  • CABG
  • Coronary Angiography
  • Coronary Artery Bypass
  • Coronary Artery Disease
  • Coronary Vessels
  • Graft Occlusion, Vascular
  • Graft failure
  • Humans
  • Patency
  • Treatment Outcome
  • Vascular Patency

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