TY - JOUR
T1 - Targeting prolyl-isomerase Pin1 prevents mitochondrial oxidative stress and vascular dysfunction: insights in patients with diabetes
AU - Paneni, Francesco
AU - Costantino, Sarah
AU - Castello, Lorenzo
AU - Battista, Rodolfo
AU - Capretti, Giuliana
AU - Chiandotto, Sergio
AU - D'Amario, Domenico
AU - Scavone, Giuseppe
AU - Villano, Angelo
AU - Rustighi, Alessandra
AU - Crea, Filippo
AU - Pitocco, Dario
AU - Lanza, Gaetano Antonio
AU - Volpe, Massimo
AU - De Sal, Giannino
AU - Luscher, Thomas
AU - Cosentino, Francesco
PY - 2014
Y1 - 2014
N2 - Diabetes is a major driver of cardiovascular disease, but the underlying mechanisms remain elusive. Prolyl-isomerase Pin1 recognizes specific peptide bonds and modulates function of proteins altering cellular homoeostasis. The present study investigates Pin1 role in diabetes-induced vascular disease.
AB - Diabetes is a major driver of cardiovascular disease, but the underlying mechanisms remain elusive. Prolyl-isomerase Pin1 recognizes specific peptide bonds and modulates function of proteins altering cellular homoeostasis. The present study investigates Pin1 role in diabetes-induced vascular disease.
KW - Diabetes mellitus
KW - Endothelial function
KW - Inflammation
KW - Oxidative stress
KW - Diabetes mellitus
KW - Endothelial function
KW - Inflammation
KW - Oxidative stress
UR - https://publicatt.unicatt.it/handle/10807/60914
UR - https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=84926674364&origin=inward
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84926674364&origin=inward
U2 - 10.1093/eurheartj/ehu179
DO - 10.1093/eurheartj/ehu179
M3 - Article
SN - 0195-668X
SP - N/A-N/A
JO - European Heart Journal
JF - European Heart Journal
IS - Maggio
ER -
